J Radiat Oncol (2017) 6:295–300 DOI 10.1007/s13566-016-0269-0 ORIGINAL RESEARCH Changes in quality of life after radiation therapy for localized prostate cancer after dissemination of intensity modulated radiation therapy 1 2,3 1,3 4 Elyn H. Wang & Shi-Yi Wang & Pamela R. Soulos & Ronald C. Chen & 3,5 1,3,6,7 1,3,6,8 Simon P. Kim & Cary P. Gross & James B. Yu Received: 5 March 2016 /Accepted: 28 July 2016 /Published online: 10 August 2016 Springer-Verlag Berlin Heidelberg 2016 Abstract were used to compare change in HRQOL from baseline to Objective It is unclear whether the adoption of intensity- follow-up as measured by physical and mental component modulated radiation therapy (IMRT) for prostate cancer is scores between patients during the two different eras. associated with improved health-related quality of life Results During the first 2 years after treatment, mental com- (HRQOL). Therefore, we examined the HRQOL of elderly ponent scores at follow-up among patients during the early era patients who had undergone external beam radiation therapy declined significantly but no such decline was observed (EBRT) during two eras: 1998–2001, when 3D-CRT was the among patients during the late era (beta = 5.18; p = 0.008 late standard of care for
Journal of Radiation Oncology – Springer Journals
Published: Aug 10, 2016
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