Changes in blood plasma volume in rats during ontogenesis

Changes in blood plasma volume in rats during ontogenesis The dynamics of blood plasma volume were studied for the first time in rats during ontogenesis. The significance of blood plasma volume is estimated in the transport of physiologically active substances to cells and target organs during development. The blood plasma volume was measured in male and female rats during embryogenesis on day 18 (E18), perinatal development on E21 and day 3 of postnatal development (P3), and postnatal development on P15 and P30. Blood plasma volume was measured using Evans Blue dye method. Body mass was determined in the same animals and correlation was estimated between the blood plasma volume and body mass. The plasma volume increased 1.9-fold from E18 to E21, 1.4-fold from E21 to P3, 2.1-fold from P3 to P15, and 3.4-fold from P15 to P30. The body mass increased 5-fold from E18 to E21, 2-fold from E21 to P3, 2.3-fold from P3 to P15, and 3.2-fold from P15 to P30. The ratio of blood plasma to body mass was the highest on E18 (19%) and decreased twice by E21. This index varied from 5.4 to 4.8% during postnatal development. No sex-related differences in these indices were found in rats. The results obtained make it possible to determine the total content of physiologically active substances on the basis of their plasma concentration and, thereby, estimate the efficiency of secretory organs. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Changes in blood plasma volume in rats during ontogenesis

Loading next page...
 
/lp/springer_journal/changes-in-blood-plasma-volume-in-rats-during-ontogenesis-GiLER40lNz
Publisher
Nauka/Interperiodica
Copyright
Copyright © 2006 by Pleiades Publishing, Inc.
Subject
Life Sciences; Developmental Biology; Animal Anatomy / Morphology / Histology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1134/S1062360406050031
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial