Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

CEUS in the differential diagnosis between biliary sludge, benign lesions and malignant lesions

CEUS in the differential diagnosis between biliary sludge, benign lesions and malignant lesions Purpose Conventional grayscale ultrasound (US) is accurate in the diagnosis of gallbladder disease (GD), but in some cases, it is not decisive. Contrast-enhanced ultrasound (CEUS) improves the diagnostic accuracy of US. The primary objective of this study is to assess the reliability of CEUS in the diagnosis of sludge; the secondary objective is to assess the ability of CEUS to diagnose cancer. Methods We retrospectively reviewed the US of 4137 patients positive for GD. In 43/4137 (1.04%), the use of could not discriminate between sludge and neoplasms. Then, we evaluated CEUS in only 39 of these patients, and in 4/43 (9%) cases it was not performable. After CEUS, the absence of enhancement was considered diagnostic for sludge, while contrast washout within 60 s diagnosed malignant lesions. Results Among the 39 patients, 16 had biliary sludge and 23 had lesions of the gallbladder wall; 9 of these were carcinomas and 14 were benign tumors. The absence of enhancement was present in 16/16 patients with sludge and in 0/23 patients with lesions of the gallbladder (sensitivity and specificity 100%). Washout was within 60 s in 9/9 gallbladder carcinomas and 2/14 benign lesions (sensitivity 100%; specificity 85%). Conclusions US is confirmed to be accurate http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Ultrasound Springer Journals

CEUS in the differential diagnosis between biliary sludge, benign lesions and malignant lesions

Download PDF
8 pages

Loading next page...
 
/lp/springer_journal/ceus-in-the-differential-diagnosis-between-biliary-sludge-benign-XpxxAuyw6C
Publisher
Springer Journals
Copyright
Copyright © 2018 by Società Italiana di Ultrasonologia in Medicina e Biologia (SIUMB)
Subject
Medicine & Public Health; Ultrasound
eISSN
1876-7931
DOI
10.1007/s40477-018-0286-5
pmid
29476456
Publisher site
See Article on Publisher Site

Abstract

Purpose Conventional grayscale ultrasound (US) is accurate in the diagnosis of gallbladder disease (GD), but in some cases, it is not decisive. Contrast-enhanced ultrasound (CEUS) improves the diagnostic accuracy of US. The primary objective of this study is to assess the reliability of CEUS in the diagnosis of sludge; the secondary objective is to assess the ability of CEUS to diagnose cancer. Methods We retrospectively reviewed the US of 4137 patients positive for GD. In 43/4137 (1.04%), the use of could not discriminate between sludge and neoplasms. Then, we evaluated CEUS in only 39 of these patients, and in 4/43 (9%) cases it was not performable. After CEUS, the absence of enhancement was considered diagnostic for sludge, while contrast washout within 60 s diagnosed malignant lesions. Results Among the 39 patients, 16 had biliary sludge and 23 had lesions of the gallbladder wall; 9 of these were carcinomas and 14 were benign tumors. The absence of enhancement was present in 16/16 patients with sludge and in 0/23 patients with lesions of the gallbladder (sensitivity and specificity 100%). Washout was within 60 s in 9/9 gallbladder carcinomas and 2/14 benign lesions (sensitivity 100%; specificity 85%). Conclusions US is confirmed to be accurate

Journal

Journal of Ultrasound – Springer Journals

Published: Feb 23, 2018

References

  • Ultrasonography in carcinoma of gallbladder: diagnostic difficults and pitfalls
    Hederstrom, E; Forsberg, L
  • Primary gallbladder carcinoma: imaging findings in 50 patients with pathologic correlation
    Franquet, T; Montes, M; Azua, R; Jimenez, FJ; Cozcolluela, R
  • Carcinoma of the gallbladder: role of sonography in diagnosis and staging
    Pandey, M; Sood, BP; Shukla, RC; Aryya, NC; Singh, S; Shukla, VK
  • Grey scale ultrasonography in the evaluation of carcinoma of the gallbladder
    Dalla Palma, L; Rizatto, G; Pozzi- Mucelli, RS; Bazzocchi, M
  • Differential diagnosis of gallbladder masses using color Doppler ultrasonography
    Hirooka, Y; Naitoh, Y; Goto, H; Furukawa, T; Ito, A; Hayakawa, T
  • Gallbladder carcinoma: color Doppler sonography
    Komatsuda, T; Ishida, H; Konno, K
  • Diagnosis of gallbladder carcinoma with gallbladder carcinoma with color Doppler USG
    Ueno, N; Tomiyana, T; Tano, S; Wada, S; Kimura, K
  • Sonographic and color Doppler morphology in gallbladder carcinoma
    Pradhan, S; Shukla, VK; Agrawal, S; Dixit, VK; Sharma, OP
  • Usefulness of contrast-enhanced ultrasonography in the differential diagnosis of polypoid gallbladder lesions
    Hattori, M; Inui, K
  • Biliary sludge
    Ko, CW; Sekijima, JH; Lee, SP
  • Biliary sludge ultrasonic appearance simulating neoplasm
    Anastasi, B; Sutherland, GR
  • Ultrasonographic difficulties and pitfalls in diagnosing primary carcinoma of the gallbladder
    Kuo, YC; Liu, JY; Sheen, IS; Yang, CY; Lin, DY; Chang Chein, CS
  • In vitro investigation of the origin of echoes with biliary sludge. Small polypoid lesions of the gallbladder differential diagnosis and surgical indications by helical computed tomography
    Filly, RA; Allen, B; Minton, MJ; Bernhoft, R; Way, LW
  • Small polypoid lesions of the gallbladder differential diagnosis and surgical indications by helical computed tomography
    Furukawa, H; Kosuge, T; Shimada, K; Yamamoto, J; Kanai, Y; Mukai, K; Iwata, R; Ushio, K
  • Application of modern imaging methods in diagnosis of gallbladder cancer
    Rodríguez-Fernández, A; Gómez-Río, M; Medina-Benítez, A; Moral, JV; Ramos-Font, C; Ramia-Angel, JM; Llamas-Elvira, JM; Ferrón-Orihuela, JA; Lardelli-Claret, P
  • SICUS and CEUS imaging in Crohn’s disease: an update
    Mocci, G; Migaleddu, V; Cabras, F; Sirigu, D; Scanu, D; Virgilio, G; Marzo, M
  • What is the role of contrast-enhanced ultrasound in the evaluation of the endoleak of aortic endoprostheses? A comparison between CEUS and CT on a widespread scale
    David, E; Cantisani, V; Grazhdani, H; Marzo, L; Venturini, L; Fanelli, F; Segni, M; Leo, N; Brunese, L; Calliada, F; Ciccariello, M; Bottari, A; Ascenti, G; D’Ambrosio, F
  • Contrast-enhanced color Doppler US in malignant portal vein thrombosis
    Ricci, P; Cantisani, V; Biancari, F; Drud, FM; Coniglio, M; Filippo, A; Fasoli, F; Passariello, R
  • Detection of hepatic metastases from colorectal cancer: prospective evaluation of gray scale US versus SonoVue® low mechanical index real time-enhanced US as compared with multidetector-CT or Gd-BOPTA-MRI
    Cantisani, V; Ricci, P; Erturk, M; Pagliara, E; Drudi, F; Calliada, F; Mortele, K; D’Ambrosio, U; Marigliano, C; Catalano, C; Marin, D; Seri, M; Longo, F; Passariello, R
  • Diagnosis of gallbladder diseases by contrast-enhanced phase-inversion harmonic ultrasonography
    Inoue, T; Kitano, M; Kuto, M
  • Differential diagnosis between benign and malignant gallbladder diseases with real-time contrast-enhanced ultrasound
    Xie, XH; Xu, HX; Xie, XY
  • Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)—update
    Claudon, M; Cosgrove, D; Albrecht, T
  • The EFSUMB guidelines and recommendations on the clinical practice of contrast enhanced ultrasound (CEUS): update 2011 on non-hepatic applications
    Piscaglia, F; Nolsøe, C; Cf, Dietrich
  • Contrast-enhanced ultrasound in the diagnosis of gallbladder diseases: a multi-center experience
    Liu, LN; Xu Hx, LuMd; Xy, Xie; Wang, W; Hu, B; Yan, K; Ding, H; Ss, Tang; Lx, Qian; Bm, Luo; Yl, Wen
  • Real-time grey scale contrast-enhanced ultrasonography in diagnosis of gallbladder cancer
    Si, Q; Qian, XL; Wang, F
  • Differential diagnosis between benign and malignant gallbladder diseases with contrast-enhanced ultrasound
    Liu, L; Zhao, Y; Zhang, Y; Liu, J
  • Meta-analysis of contrast-enhanced ultrasonography for the detection of gallbladder carcinoma
    Wang, W; Fei, Y; Wang, F
  • Natural history of polypoid lesions in the gallbladder
    Moriguchi, H; Tazawa, J; Hayashi, Y
  • Primary gallbladder cancer: recognition of risk factors and the role of prophylactic cholecystectomy
    Sheth, S; Berford, A; Chopra, S
  • Image-directed and color Doppler studies of gallbladder tumors
    Li, D; Dong, BW; Wu, YL; Yan, K
  • Contrast enhanced sonography of the gallbladder: a tool in the diagnosis of cholecystitis?
    Adamietz, B; Wenkel, E; Uder, M; Meyer, T; Schneider, I; Dimmler, A; Bautz, W; Janka, R
  • Differential diagnosis of gallbladder diseases with contrast-enhanced harmonic gray scale ultrasonography
    Numata, K; Oka, H; Morimoto, M
  • Contrast-enhanced ultrasonography improves the diagnostic specificity for gallbladder-confined focal tumors
    Zhuang, B; Li, W; Wang, W
  • Ultrasound evaluation of liver fibrosis: preliminary experience with acoustic structure quantification (ASQ) software
    Ricci, P; Marigliano, C; Cantisani, V; Porfiri, A; Marcantonio, A; Lodise, P; D’Ambrosio, U; Labbadia, G; Maggini, E; Mancuso, E; Panzironi, G; Segni, M; Furlan, C; Masciangelo, R; Taliani, G
  • EFSUMB guidelines and recommendations on the clinical use of liver ultrasound elastography, update 2017 (Long Version)
    Dietrich, CF; Bamber, J; Berzigotti, A
  • The use of real-time elastography in the assessment of gallbladder polyps: preliminary observations
    Teber, MA; Tan, S; Dönmez, U; İpek, A; Uçar, AE; Yıldırım, H; Aslan, A; Arslan, H