Cellular apoptosis susceptibility gene Capts maps to mouse Chromosome 2

Cellular apoptosis susceptibility gene Capts maps to mouse Chromosome 2 M4mmafian Brief Data Reports IncorporatIng Mouse Genome Mammalian Genome 9, 411-414 (1998). © Springer-Verlag New York Inc. 1998 20g13 [3]. In humans, this region is known to harbor amplifica- Cellular apoptosis susceptibility gene Capts tions that correlate with aggressive breast cancer. In fact, CAPTS maps to mouse Chromosome 2 has been described as part of aberrant human chromosome 20q in several breast and colon cancer cell lines [3]. CAPTS mRNA is Maria de Miguel,* John M. Centanni, highly expressed in tissues that contain actively dividing cells, such as human testis and fetal liver, and is elevated in lymphoid Ganesan Gopalan, Debra J. Gilbert, Neal G. Copeland, tissues, as well as in several tumor cell lines [1]. In culture, CAPTS Nancy A. Jenkins, Peter J. Donovan expression correlates with the proliferative activity of human fi- Mammalian Genetics Laboratory, ABL-Basic Research Program, broblasts [1], indicating an important role in cell division. CAPTS NCI-FCRDC, PO BOX B, Bldg 539, Frederick, Maryland 21702-1201, reduction in MCF-7 breast cancer cells confers resistance to the USA Pseudomonas diphtheria apoptotic effects of toxin, toxin, and tu- mor necrosis factors alpha and beta [4]. Human CAPTS has been Received: 20 September 1997 / Accepted: 30 December 1997 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

Cellular apoptosis susceptibility gene Capts maps to mouse Chromosome 2

Loading next page...
Copyright © 1998 by Springer-Verlag
Life Sciences; Cell Biology; Anatomy; Zoology
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial