Curr Diab Rep (2017) 17:137 https://doi.org/10.1007/s11892-017-0956-2 MACROVASCULAR COMPLICATIONS IN DIABETES (VR ARODA AND A GETANEH, SECTION EDITORS) Cardiometabolic Risk in PCOS: More than a Reproductive Disorder 1,2 Laura C. Torchen Springer Science+Business Media, LLC 2017 Abstract Introduction Purpose of Review Polycystic ovary syndrome (PCOS) is di- agnosed by its characteristic reproductive features. However, Polycystic ovary syndrome (PCOS) is among the most PCOS is also associated with metabolic abnormalities, includ- common endocrine disorders in women of reproductive ing insulin resistance and β-cell dysfunction. The severity of age with prevalence of 5–15%, depending on the diag- these abnormalities varies according to the reproductive phe- nostic criteria applied . PCOS is defined by its notype, with the so-called NIH or classic phenotype confer- reproductive features of hyperandrogenism, chronic ring the greatest metabolic risk. The increased risk for type 2 oligoanovulation, and/or polycystic ovarian morphology diabetes (T2D) is well established among affected women (PCOM) . However, it has become increasingly evident with the NIH phenotype, but whether PCOS also confers an over the past 35 years that PCOS is also a major meta- increased risk for cardiovascular events remains unknown. bolic disorder associated with substantial defects in insu- Recent Findings Recent studies in
Current Diabetes Reports – Springer Journals
Published: Nov 11, 2017
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