Reactions 1704, p85 - 2 Jun 2018 Bronchomediastinal fistula: case report The 54-year-old man developed bronchomediastinal fistula during chemotherapy with carboplatin and paclitaxel [taxol] for squamous cell lung cancer. The man, who had squamous cell lung cancer, underwent lower left lobectomy. One year later, he presented recurrence at the ganglion level and received chemotherapy and radiotherapy for three months. After one year of stabilisation, he developed haemoptysis with relapse in the posterior wall of the main right bronchus. Consequently, he was started on carboplatin [route and dosage not stated] and paclitaxel. Approximately one month after the last cycle of chemotherapy, he presented to the emergency department because of progressive dyspnoea and was hospitalised. Radiological findings revealed adenopathic mass- conglomerate of necrotic appearance at the right parahilar and subcarinal mediastinal level along with a fistulous tract that communicated necrotic subcarinal lymphadenopathies with the bronchus intermedius. Flexible bronchoscopy confirmed the neoplastic involvement with broncho-mediastinal fistula in the bronchus intermedius posterior wall. Ten days later, the man’s fistula was sealed by rigid bronchoscope with bovine serum albumin/glutaral under general anaesthesia. During examination, the previous fistulous opening was not visible, which had closed spontaneously. Fourteen days after admission, he was discharged home with clinical improvement; however, he required home oxygen therapy and follow-up by the palliative unit. Two months later, he died at home because of overall deterioration secondary to the evolution of his neoplastic disease. Author comment: "Tracheomediastinal fistulas appear mainly related to lung cancer, and particularly to lymphoma, appearing secondary to necrosis caused by chemotherapy or radiotherapy in adenopathies in close contact with the tracheal wall." Hurtado EJS, et al. Bronchomediastinal fistula with spontaneous resolution in a patient with lung cancer. Current Respiratory Medicine Reviews 13: 178-181, No. 3, Sep 2017. Available from: URL: http:// doi.org/10.2174/1573398X13666170522183920 - Spain 803323129 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
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