Reactions 1704, p86 - 2 Jun 2018 Thrombocytopenia: case report In a retrospective chart review of 27 women (aged 45 76 years), one woman was described [age not stated], who developed thrombocytopenia following treatment with carboplatin and paclitaxel for ovarian cancer [routes, duration of treatments to reaction onset and outcome not stated]. The woman, who had stage I/II ovarian cancer, started receiving treatment with paclitaxel 100 mg/m on days 1 and 11 along with carboplatin (AUC 6) every three weeks. She developed grade 3 thrombocytopenia. Author comment: "Stage I and II ovarian cancer patients who only received adjuvant divided-dose therapy, four required dose reductions, four had grade 4 neutropenia, and one had grade 3 thrombocytopenia." Kudlowitz D, et al. Carboplatin (every 21 days) and divided-dose paclitaxel (days 1, 11): rationale and tolerance in chemotherapy naive women with high-grade epithelial cancers of Mullerian origin. Cancer Chemotherapy and Pharmacology 81: 847-851, No. 5, May 2018. Available from: URL: https://doi.org/10.1007/ s00280-018-3559-y - USA 803323454 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
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