Capecitabine

Capecitabine Reactions 1704, p78 - 2 Jun 2018 Thrombocytopenia: case report In a study of 25 patients, a patient [age and sex not stated] was described, who developed thrombocytopenia during treatment with capecitabine [duration of treatment to reaction onset not stated]. The patient, who had rectal carcinoma, received neoadjuvant chemo-radiotherapy. The patient received oral capecitabine 825 mg/m in two daily doses along with radiotherapy 2Gy per day. The patient received a total dose of 44Gy and completed radiotherapy without any complications. However, while receiving capecitabine chemotherapy, the patient developed grade III thrombocytopenia. As a result, the patient’s capecitabine chemotherapy was discontinued prematurely [outcome not stated]. Author comment: "Concomitant chemotherapy was discontinued prematurely in one patient because of grade III thrombocytopenia." "[C]oncomitant chemotherapy was discontinued prematurely in one patient because of hematological toxicity." Richter I, et al. The prognostic effect of neoadjuvant chemoradiotherapy on the change of PD-L1 expression in patients with locally advanced rectal adenocarcinoma. Journal of B. U. ON: Official Journal of the Balkan Union of Oncology 22: 875-881, No. 4, Jul-Aug 2017. Available from: URL: https:// www.jbuon.com/pdfs/875-881.pdf - Czech Republic 803323269 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Capecitabine

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46721-8
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p78 - 2 Jun 2018 Thrombocytopenia: case report In a study of 25 patients, a patient [age and sex not stated] was described, who developed thrombocytopenia during treatment with capecitabine [duration of treatment to reaction onset not stated]. The patient, who had rectal carcinoma, received neoadjuvant chemo-radiotherapy. The patient received oral capecitabine 825 mg/m in two daily doses along with radiotherapy 2Gy per day. The patient received a total dose of 44Gy and completed radiotherapy without any complications. However, while receiving capecitabine chemotherapy, the patient developed grade III thrombocytopenia. As a result, the patient’s capecitabine chemotherapy was discontinued prematurely [outcome not stated]. Author comment: "Concomitant chemotherapy was discontinued prematurely in one patient because of grade III thrombocytopenia." "[C]oncomitant chemotherapy was discontinued prematurely in one patient because of hematological toxicity." Richter I, et al. The prognostic effect of neoadjuvant chemoradiotherapy on the change of PD-L1 expression in patients with locally advanced rectal adenocarcinoma. Journal of B. U. ON: Official Journal of the Balkan Union of Oncology 22: 875-881, No. 4, Jul-Aug 2017. Available from: URL: https:// www.jbuon.com/pdfs/875-881.pdf - Czech Republic 803323269 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

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