Candida auris: What We Need to Know in Healthcare Settings

Candida auris: What We Need to Know in Healthcare Settings Purpose of review Candida auris is an emerging pathogen characterized for its difficult identification, rapid nosocomial spread, and limited treatment options. Data is currently limited; however, this will change as the pathogen’s prevalence increases. The goal of this review is to provide a concise summary of the available data to manage a possible C. auris infection. Recent findings Candida auris has been rapidly spreading globally and has been evading popular identification methods with MALDI-TOF being the only successful modality as long as the “research use only” database is used. Echinocandins are the treatment of choice; however, all isolates should have susceptibilities performed as there have been reports of resistance to all antifungal classes. Several hospital outbreaks have occurred; thus, all patients should be isolated with appropriate terminal cleaning. Summary Atypical or suspicious Candida isolates should be identified by MALDI-TOF. Most Candida auris strains are resistant to azoles; therefore, the suggested empirical treatment is an echinocandin. Echinocandin-resistant strains have been reported, and in those cases, a polyene is preferred. Strict contact precautions are recommended while in the hospital due to high levels of nosocomial transmission. Introduction With a growing immunosuppressed population and environments, a shift towards multi-drug resistance cre- more http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Treatment Options in Infectious Diseases Springer Journals

Candida auris: What We Need to Know in Healthcare Settings

Loading next page...
 
/lp/springer_journal/candida-auris-what-we-need-to-know-in-healthcare-settings-smWtyMy9sO
Publisher
Springer US
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Infectious Diseases
eISSN
1534-6250
D.O.I.
10.1007/s40506-018-0168-6
Publisher site
See Article on Publisher Site

Abstract

Purpose of review Candida auris is an emerging pathogen characterized for its difficult identification, rapid nosocomial spread, and limited treatment options. Data is currently limited; however, this will change as the pathogen’s prevalence increases. The goal of this review is to provide a concise summary of the available data to manage a possible C. auris infection. Recent findings Candida auris has been rapidly spreading globally and has been evading popular identification methods with MALDI-TOF being the only successful modality as long as the “research use only” database is used. Echinocandins are the treatment of choice; however, all isolates should have susceptibilities performed as there have been reports of resistance to all antifungal classes. Several hospital outbreaks have occurred; thus, all patients should be isolated with appropriate terminal cleaning. Summary Atypical or suspicious Candida isolates should be identified by MALDI-TOF. Most Candida auris strains are resistant to azoles; therefore, the suggested empirical treatment is an echinocandin. Echinocandin-resistant strains have been reported, and in those cases, a polyene is preferred. Strict contact precautions are recommended while in the hospital due to high levels of nosocomial transmission. Introduction With a growing immunosuppressed population and environments, a shift towards multi-drug resistance cre- more

Journal

Current Treatment Options in Infectious DiseasesSpringer Journals

Published: May 28, 2018

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off