Cadmium-induced oxidative stress in the bivalve Modiolus modiolus is studied from the standpoint of the universality of the mechanism of free-radical oxidation. The kinetics of cadmium accumulation by the bivalve was revealed in a laboratory experiment. The gills accumulated higher Cd levels than the digestive gland. In the process of cadmium accumulation, there was an increase in lipid peroxidation products (malondialdehyde and lipofuscin) and a reduction in the total oxiradical scavenging capacity (TOSC). Cadmium induces oxidative stress in molluscan tissues through damage to the antioxidation system. Thus, TOSC can provide a useful biochemical indicator of early pathological changes in the cell or the organism, as well as of the environmental effects of heavy metal pollution.
Russian Journal of Marine Biology – Springer Journals
Published: Nov 14, 2005
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