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Do Lee, A. Goldberg (1998)
Proteasome inhibitors: valuable new tools for cell biologists.Trends in cell biology, 8 10
M. Lawrence, E. Suzuki, J. Varghese, P. Davis, A. Donkelaar, P. Tulloch, P. Colman (1990)
The three‐dimensional structure of the seed storage protein phaseolin at 3 A resolution.The EMBO Journal, 9
J.M. Lord, J. Davey, L. Frigerio, L.M. Roberts (2000)
Endoplasmic reticulum-associated protein degradationSem. Cell Dev. Biol., 11
L. Gómez, M. Chrispeels (1993)
Tonoplast and Soluble Vacuolar Proteins Are Targeted by Different Mechanisms.The Plant cell, 5
L. Hoffman, D. Donaldson, E. Herman (1988)
A modified storage protein is synthesized, processed, and degraded in the seeds of transgenic plantsPlant Molecular Biology, 11
G. Fenteany, R. Standaert, William Lane, S. Choi, E. Corey, S. Schreiber (1995)
Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystinScience, 268
L. Frigerio, Alessandra Pastres, Alessandra Prada, A. Vitale (2001)
Influence of KDEL on the Fate of Trimeric or Assembly-Defective Phaseolin: Selective Use of an Alternative Route to VacuolesPlant Cell, 13
C. Ritzenthaler, A. Nebenfuhr, A. Movafeghi, C. Stussi-Garaud, L. Behnia, P. Pimpl, L.A. Staehelin, D.G. Robinson (2002)
Re-evaluation of the effects of brefeldin A on plant cells using tobacco Bright Yellow 2 cells expressing Golgi-targeted green fluorescent protein and COPI antiseraPlant Cell, 14
Michael Lawrence, Tina Izard, M. Beuchat, R. Blagrove, Peter Colman (1994)
Structure of phaseolin at 2.2 A resolution. Implications for a common vicilin/legumin structure and the genetic engineering of seed storage proteins.Journal of molecular biology, 238 5
L. Frigerio, M. Virgilio, Alessandra Prada, F. Faoro, A. Vitale (1998)
Sorting of Phaseolin to the Vacuole Is Saturable and Requires a Short C-Terminal PeptidePlant Cell, 10
S. Nishikawa, Sheara Fewell, Y. Kato, J. Brodsky, T. Endo (2001)
Molecular Chaperones in the Yeast Endoplasmic Reticulum Maintain the Solubility of Proteins for Retrotranslocation and DegradationThe Journal of Cell Biology, 153
Shilpa Vashist, Woong Kim, W. Belden, Eric Spear, C. Barlowe, D. Ng (2001)
Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein foldingThe Journal of Cell Biology, 155
E. Jarosch, U. Lenk, T. Sommer (2003)
Endoplasmic reticulum-associated protein degradation.International review of cytology, 223
L. Frigerio, A. Vitale, J. Lord, A. Ceriotti, L. Roberts (1998)
Free Ricin A Chain, Proricin, and Native Toxin Have Different Cellular Fates When Expressed in Tobacco Protoplasts*The Journal of Biological Chemistry, 273
Francesca Lupattelli, E. Pedrazzini, R. Bollini, A. Vitale, A. Ceriotti (1997)
The Rate of Phaseolin Assembly Is Controlled by the Glucosylation State of Its N-Linked Oligosaccharide Chains.The Plant cell, 9
L. Frigerio, O. Foresti, D. Felipe, J. Neuhaus, A. Vitale (2001)
The C-terminal tetrapeptide of phaseolin is sufficient to target green fluorescent protein to the vacuoleJournal of Plant Physiology, 158
J. Dyer, J. Nelson, N. Murai (1993)
Strategies for selecting mutation sites for methionine enhancement in the bean seed storage protein phaseolinJournal of Protein Chemistry, 12
A. Cola, L. Frigerio, J. Lord, A. Ceriotti, L. Roberts (2001)
Ricin A chain without its partner B chain is degraded after retrotranslocation from the endoplasmic reticulum to the cytosol in plant cellsProceedings of the National Academy of Sciences of the United States of America, 98
W. Bonner, R. Laskey (1974)
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.European journal of biochemistry, 46 1
E. Pedrazzini, Giovanna Giovinazzo, A. Bielli, M. Virgilio, L. Frigerio, M. Pesca, O. Faoro, R. Bollini, A. Ceriotti, Alessandro Vitaleas (1997)
Protein quality control along the route to the plant vacuole.The Plant cell, 9
L. Tabe, L. Tabe, T. Wardley-Richardson, T. Wardley-Richardson, A. Ceriotti, A. Ceriotti, A. Aryan, A. Aryan, Warren McNabb, Warren McNabb, Andrew Moore, Andrew Moore, T?J?V Higgins, T?J?V Higgins (1995)
A biotechnological approach to improving the nutritive value of alfalfa.Journal of animal science, 73 9
C. Hammond, A. Helenius (1995)
Quality control in the secretory pathway.Current opinion in cell biology, 7 4
C. Ritzenthaler, A. Nebenführ, A. Movafeghi, C. Stussi‐Garaud, Leila Behnia, P. Pimpl, L. Staehelin, D. Robinson (2002)
Reevaluation of the Effects of Brefeldin A on Plant Cells Using Tobacco Bright Yellow 2 Cells Expressing Golgi-Targeted Green Fluorescent Protein and COPI Antisera Online version contains Web-only data. Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.The Plant Cell Online, 14
K. Törmäkangas, Jane Hadlington, P. Pimpl, S. Hillmer, F. Brandizzi, T. Teeri, J. Denecke (2001)
A Vacuolar Sorting Domain May Also Influence the Way in Which Proteins Leave the Endoplasmic ReticulumThe Plant Cell Online, 13
E. Pedrazzini, G. Giovinazzo, R. Bollini, A. Ceriotti, A. Vitale (1994)
Binding of BiP to an assembly‐defective protein in plant cellsPlant Journal, 5
R. Bollini, W. Wilden, M. Chrispeels (1982)
A precursor of the reserve‐protein, phaseolin, is transiently associated with the endoplasmic reticulum of developing Phaseolus vulgaris cotyledonsPhysiologia Plantarum, 55
A. Vitale, M. Zoppè, R. Bollini (1989)
Mannose analog 1-deoxymannojirimycin inhibits the Golgi-mediated processing of bean storage glycoproteins.Plant physiology, 89 4
B. Phillipson, P. Pimpl, P. Pimpl, L. daSilva, A. Crofts, J. Taylor, A. Movafeghi, D. Robinson, J. Denecke (2001)
Secretory Bulk Flow of Soluble Proteins Is Efficient and COPII DependentThe Plant Cell Online, 13
J. Dyer, J. Nelson, N. Murai (1995)
Extensive modifications for methionine enhancement in the β-barrels do not alter the structural stability of the bean seed storage protein phaseolinJournal of Protein Chemistry, 14
K. Müntz (1998)
Deposition of storage proteinsPlant Molecular Biology, 38
L. Ellgaard, M. Molinari, A. Helenius (1999)
Setting the standards: quality control in the secretory pathwayScience, 286
A. Vitale, A. Bielli, A. Ceriotti (1995)
The Binding Protein Associates with Monomeric Phaseolin, 107
L. D’amico, B. Valsasina, M. Daminati, M. Fabbrini, G. Nitti, R. Bollini, A. Ceriotti, A. Vitale (1992)
Bean homologs of the mammalian glucose-regulated proteins: induction by tunicamycin and interaction with newly synthesized seed storage proteins in the endoplasmic reticulum.The Plant journal : for cell and molecular biology, 2 4
In an attempt to increase the content in essential amino acids methionine and tryptophan of the trimeric storage protein phaseolin, we fused a Met- and Trp-rich sequence to the C-terminus of a phaseolin variant lacking its vacuolar sorting signal, with the aim to target the protein for secretion and accumulation into the apoplast. The fate of the mutant protein, denominated Y3, was studied in transiently transfected tobacco protoplasts. We report that the presence of the additional sequence causes structural defects which inhibit trimerization and lead to partial aggregation of Y3. The protein interacts with the ER chaperone BiP prior to being degraded very rapidly, in a process that does not require vesicular transport from the ER. The rate of degradation of Y3 is higher than that observed for another assembly defective mutant of phaseolin, Δ360, which remains monomeric and does not aggregate. This indicates that the plant ER quality control machinery can dispose of defective proteins with different kinetics and perhaps mechanisms, depending on the nature of their defect.
Plant Molecular Biology – Springer Journals
Published: Oct 7, 2004
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