Bupropion Versus Sertraline in the Treatment of Depressive Patients with Binge Eating Disorder: Retrospective Cohort Study

Bupropion Versus Sertraline in the Treatment of Depressive Patients with Binge Eating Disorder:... This study sought to compare Bupropion versus Sertraline in the treatment of depressed patients with Binge Eating Disorder (BED) prescribed off-label. Medical records of outpatients with diagnosis of BED and Depression (DSM-IV-TR criteria) were selected: 15 patients were treated with bupropion 150 mg/per day, and 15 with sertraline 200 mg/per day. During the screening and control visits (2°–6°–14°–24° week), the selected patients were first weighed and then evaluated using the following questionnaires: Binge Eating Disorder-Clinical Interview (BEDCI), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory X (STAI-X) and Arizona Sexual Experience Scale (ASEX). Both drugs reduced anxious-depressive symptoms and binge frequency: Bupropion showed a better effectiveness in reducing weight and improving sexual performances; weight loss related to it was proportional to the body mass index. Bupropion may be associated with more weight loss in BED, depressed patients than sertraline. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychiatric Quarterly Springer Journals

Bupropion Versus Sertraline in the Treatment of Depressive Patients with Binge Eating Disorder: Retrospective Cohort Study

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Publisher
Springer US
Copyright
Copyright © 2011 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Psychiatry; Public Health; Sociology, general
ISSN
0033-2720
eISSN
1573-6709
D.O.I.
10.1007/s11126-011-9192-0
Publisher site
See Article on Publisher Site

Abstract

This study sought to compare Bupropion versus Sertraline in the treatment of depressed patients with Binge Eating Disorder (BED) prescribed off-label. Medical records of outpatients with diagnosis of BED and Depression (DSM-IV-TR criteria) were selected: 15 patients were treated with bupropion 150 mg/per day, and 15 with sertraline 200 mg/per day. During the screening and control visits (2°–6°–14°–24° week), the selected patients were first weighed and then evaluated using the following questionnaires: Binge Eating Disorder-Clinical Interview (BEDCI), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory X (STAI-X) and Arizona Sexual Experience Scale (ASEX). Both drugs reduced anxious-depressive symptoms and binge frequency: Bupropion showed a better effectiveness in reducing weight and improving sexual performances; weight loss related to it was proportional to the body mass index. Bupropion may be associated with more weight loss in BED, depressed patients than sertraline.

Journal

Psychiatric QuarterlySpringer Journals

Published: Sep 17, 2011

References

  • Gender differences in outcome of eating disorders: A retrospective cohort study
    Støving, RK; Andries, A; Brixen, K
  • Comorbidity and age of onset of eating disorders in gay men, lesbians, and bisexuals
    Feldman, MB; Meyer, IH
  • Comparison of binge eating disorder and bulimia nervosa in a community sample
    Striengel-Moore, RH; Cachelin, FM; Dohm, FA
  • Binge Eating Disorder treatment: A systematic review of randomized controlled trials
    Brownley, KA; Berkman, ND; Sedway, JA
  • A 12 to 24 weeks pilot study of sertraline treatment in obese women binge eaters
    Leonbruni, P; Pierò, A; Brustolin, A
  • High dose escitalopram in the treatment of binge eating disorder with obesity: A placebo controlled monotherapy trial
    Guerdjikova, AI; McElroy, SL; Kotwal, R

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