Brain-derived neurotrophic factor gene (BDNF) polymorphism among Moscow citizens

Brain-derived neurotrophic factor gene (BDNF) polymorphism among Moscow citizens Recent studies showed that brain-derived neurotrophic factor (BDNF) can participate in pathogenesis of various CNS disorders, being connected with proliferation, differentiation, and survival of neurons. In present study, analysis of occurrence rate was performed for three single nucleotide polymorphisms (SNPs) located in BDNF gene (rs6267 (A/G) allele A—0.265; rs2049046 (A/T) allele A—0.407; rs11030107 (A/G) allele A—0.872) in randomized selection of Moscow citizens. Linkage disequilibrium of rs6165 and rs2049046 loci was shown. Differences in allele frequencies in studied selection and populations of other regions were discovered. Russian Journal of Genetics Springer Journals

Brain-derived neurotrophic factor gene (BDNF) polymorphism among Moscow citizens

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Springer US
Copyright © 2013 by Pleiades Publishing, Inc.
Biomedicine; Human Genetics; Animal Genetics and Genomics; Microbial Genetics and Genomics
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