Book Review

Book Review Arch Virol (2004) 149: 1257–1258 DOI 10.1007/s00705-004-0343-6 Polansky, H.: Microcompetition with Foreign DNA and the Origin of Chronic Disease. 543pp, The Center for the Biology of Chronic Disease, Rochester, New York, 2003. ISBN 0-9740463-0-2 Paperback $79.99. No student of biomedical sciences could ignore the appearance of a new theory offering explanations for the origin of chronic diseases. Systematic testing and better understanding of a framework outlined by such a theory may lead to a paradigm shift in scientific view on the nature of “health” as well as causality of “disease.” According to a new book, Microcompetition with Foreign DNA and the Origin of Chronic Disease, by Dr. Hanan Polansky, the current paradigm holds that viral proteins are the sole mediators of the viral effect on the host cell, in other words, “no viral protein, no effect.” Since “no viral proteins,” or almost “no viral proteins,” is a characteristic of a latent viral infection, the current view holds that a latent viral infection should be mostly harmless. In contrast with the current “viral protein”-dependent paradigm, the book presents a newly discovered, “viral protein”-independent effect, called microcompetition. In brief, the effect of “microcompetition” can be described as a sequence of elementary Archives of Virology Springer Journals

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