Osteoporos Int (2017) 28:2601–2610 DOI 10.1007/s00198-017-4097-x ORIGINAL ARTICLE Bone mineral density at femoral neck and lumbar spine in adults with type 1 diabetes: a meta-analysis and review of the literature 1 2 3 4 1 1 V. N. Shah & K. K. Harrall & C. S. Shah & T. L. Gallo & P. Joshee & J. K. Snell-Bergeon & W. M. Kohrt Received: 7 March 2017 /Accepted: 15 May 2017 /Published online: 3 June 2017 International Osteoporosis Foundation and National Osteoporosis Foundation 2017 Abstract spine between subjects with T1D and controls adjusting for Summary We performed a meta-analysis to evaluate the fem- age, sex, and dual x-ray absorptiometry (DXA) instruments. oral neck and lumbar spine bone mineral density (BMD) in Results Sixteen studies met the inclusion criteria. The femoral adults with type 1 diabetes (T1D) compared with controls. neck BMD was modestly lower in adults with T1D compared Adults with T1D have modestly lower BMD at femoral neck to controls (−0.055 g/cm ; 95% CI: −0.065, −0.045). There and lumbar spine than adults without diabetes. were no differences in lumbar spine BMD between adults Introduction Fracture risk is four to sixfold higher in adults with T1D and controls (0.0062
Osteoporosis International – Springer Journals
Published: Jun 3, 2017
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