Bone and Calcified Soft Tissue Metastases of Medullary Thyroid Carcinoma Better Characterized on 18F-Fluoride PET/CT than on 68Ga-Dotatate PET/CT

Bone and Calcified Soft Tissue Metastases of Medullary Thyroid Carcinoma Better Characterized on... Herein, we report a case of a 19-year-old man with multiple endocrine neoplasia type 2B (MEN2B) and medullary thyroid carcinoma (MTC) diagnosed when he was 12 years of age. The patient had previously undergone total thyroidectomy, cervical radiotherapy, and chemotherapy. He progressed with known bone, pulmonary, and lymph node metastases and was scanned with 18 18 68 F-fluoride ( F-NaF) and Ga-dotatate whole-body positron emission tomography/computed tomography (PET/CT) for met- astatic disease monitoring. We found that the MTC bone metastases and soft tissue calcified metastases were better characterized 18 68 18 on F-NaF PET/CT than on Ga-dotatate PET/CT. This case illustrates that the F-NaF PET/CT could be helpful not only to the detection of bone metastases but also to the detection of calcified soft tissue metastases in patients with MTC. 68 18 18 . . . . . Keywords Medullary thyroid carcinoma Gallium-68 Ga F F-NaF PET/CT Introduction the postoperative follow-up, if the serum calcitonin level ex- ceeds 150 pg/mL, patients should be evaluated by imaging Medullary thyroid carcinoma (MTC) is a rare neuroendocrine procedures, including neck ultrasonography (US), chest com- malignancy originating from the thyroid parafollicular C cells puted tomography (CT), contrast-enhanced magnetic reso- and, according to recent http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nuclear Medicine and Molecular Imaging Springer Journals

Bone and Calcified Soft Tissue Metastases of Medullary Thyroid Carcinoma Better Characterized on 18F-Fluoride PET/CT than on 68Ga-Dotatate PET/CT

Loading next page...
 
/lp/springer_journal/bone-and-calcified-soft-tissue-metastases-of-medullary-thyroid-6JcoKxD9JW
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2018 by Korean Society of Nuclear Medicine
Subject
Medicine & Public Health; Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology
ISSN
1869-3474
eISSN
1869-3482
D.O.I.
10.1007/s13139-018-0527-8
Publisher site
See Article on Publisher Site

Abstract

Herein, we report a case of a 19-year-old man with multiple endocrine neoplasia type 2B (MEN2B) and medullary thyroid carcinoma (MTC) diagnosed when he was 12 years of age. The patient had previously undergone total thyroidectomy, cervical radiotherapy, and chemotherapy. He progressed with known bone, pulmonary, and lymph node metastases and was scanned with 18 18 68 F-fluoride ( F-NaF) and Ga-dotatate whole-body positron emission tomography/computed tomography (PET/CT) for met- astatic disease monitoring. We found that the MTC bone metastases and soft tissue calcified metastases were better characterized 18 68 18 on F-NaF PET/CT than on Ga-dotatate PET/CT. This case illustrates that the F-NaF PET/CT could be helpful not only to the detection of bone metastases but also to the detection of calcified soft tissue metastases in patients with MTC. 68 18 18 . . . . . Keywords Medullary thyroid carcinoma Gallium-68 Ga F F-NaF PET/CT Introduction the postoperative follow-up, if the serum calcitonin level ex- ceeds 150 pg/mL, patients should be evaluated by imaging Medullary thyroid carcinoma (MTC) is a rare neuroendocrine procedures, including neck ultrasonography (US), chest com- malignancy originating from the thyroid parafollicular C cells puted tomography (CT), contrast-enhanced magnetic reso- and, according to recent

Journal

Nuclear Medicine and Molecular ImagingSpringer Journals

Published: Jun 4, 2018

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off