Reactions 1704, p72 - 2 Jun 2018 Thrombocytopenia and anaemia: 2 case reports In a single center retrospective study involving 18 female patients, two female patients [ages not stated] were described, who developed thrombocytopenia (1 female patient) and anaemia (1 female patient) during treatment with bleomycin, cisplatin and etoposide for advanced yolk sac tumour [routes, duration of treatments to reaction onsets and outcomes not stated]. The female patients, who had inoperable advanced yolk sac tumour, started receiving neoadjuvant chemotherapy with bleomycin, cisplatin and etoposide. Bleomycin was administered at a dose of 15 mg/m per day on days 1 3, etoposide at a dose of 80 mg/m per day on days 1 5 and cisplatin at a dose of 20 mg/m per day on days 1 5. The female patients, who desired to preserve their fertility, were scheduled to undergo fertility-sparing surgery upon completion of the neoadjuvant chemotherapy. The cycles were repeated every 21 days. However, while receiving the neoadjuvant chemotherapy, one female patient developed grade 3-4 thrombocytopenia and another female patient developed grade 3 anaemia. The patient with thrombocytopenia required platelet transfusion. Author comment: "Grades 3 4 thrombocytopenia was observed in 3 cases, and platelet transfusion was indicated for 1 patient. Grade 3 anemia was observed in 1 patient." Zhang G-Y, et al. Neoadjuvant Bleomycin, Etoposide, and Cisplatin (BEP) Chemotherapy in the Treatment of Extensively Advanced Yolk Sac Tumors: A Single Center Experience. International Journal of Gynecological Cancer 28: 713-720, No. 4, May 2018. Available from: URL: http://doi.org/10.1097/ IGC.0000000000001209 - China 803323940 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera