Bleomycin

Bleomycin Reactions 1704, p71 - 2 Jun 2018 Flagellated dermatitis: case report An 8-year-old girl developed flagellated dermatitis during treatment with bleomycin [dosage not stated]. The girl who had a history of primary intracranial mixed germ cell tumour (sellar and suprasellar) and secondary panhypopituitarism received chemotherapy with IV bleomycin for three days. However, after two days, she developed intermittent pruritus associated with erythematous and pigmented maculae of linear distribution, followed by a flagellated pattern, with isolated signs of excoriation, in the abdominal region and upper back [duration of treatment to reaction onset not clearly stated]. She was diagnosed with flagellated dermatitis. The girl was treated with unspecified mild topical corticosteroids for 10 days, which led to satisfactory improvement in the symptoms. Author comment: "Flagellated dermatitis is an infrequent pathology, with characteristic skin lesions, which is developed due to the use of bleomycin." Andres Stevens Gonzalez J, et al. Bleomycin-induced Flagellated dermatitis: A case report. Revista Chilena de Pediatria 89: 257-260, No. 2, Apr 2018. Available from: URL: http://doi.org/10.4067/S0370-41062018000200257 [Spanish; summarised from an English abstract] - Chile 803322983 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Bleomycin

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46714-9
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p71 - 2 Jun 2018 Flagellated dermatitis: case report An 8-year-old girl developed flagellated dermatitis during treatment with bleomycin [dosage not stated]. The girl who had a history of primary intracranial mixed germ cell tumour (sellar and suprasellar) and secondary panhypopituitarism received chemotherapy with IV bleomycin for three days. However, after two days, she developed intermittent pruritus associated with erythematous and pigmented maculae of linear distribution, followed by a flagellated pattern, with isolated signs of excoriation, in the abdominal region and upper back [duration of treatment to reaction onset not clearly stated]. She was diagnosed with flagellated dermatitis. The girl was treated with unspecified mild topical corticosteroids for 10 days, which led to satisfactory improvement in the symptoms. Author comment: "Flagellated dermatitis is an infrequent pathology, with characteristic skin lesions, which is developed due to the use of bleomycin." Andres Stevens Gonzalez J, et al. Bleomycin-induced Flagellated dermatitis: A case report. Revista Chilena de Pediatria 89: 257-260, No. 2, Apr 2018. Available from: URL: http://doi.org/10.4067/S0370-41062018000200257 [Spanish; summarised from an English abstract] - Chile 803322983 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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