Blastic plasmacytoid dendritic cell neoplasm: a pathological illustration of two clinical cases

Blastic plasmacytoid dendritic cell neoplasm: a pathological illustration of two clinical cases Ann Hematol (2017) 96:1769–1770 DOI 10.1007/s00277-017-3079-6 LETTER TO THE EDITOR Blastic plasmacytoid dendritic cell neoplasm: a pathological illustration of two clinical cases 1 2 3 4 2,5 Jessica C. Griffin & Nayef Aqel & Wenchee Siow & Marquita Camilleri & Robert Ayto Received: 10 June 2017 /Accepted: 23 July 2017 /Published online: 1 August 2017 Springer-Verlag GmbH Germany 2017 Dear Editor, and negative for CD34, CD117, MPO and CD33, compatible Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a with BPDCN (Fig. 1, d2). Infiltrative cells on lymph node rare aggressive disease characterised by clonal proliferation of biopsy were positive for CD4, CD56 and CD123. plasmacytoid dendritic cell precursors [1]. Defined as a mye- The patient commenced FLAG-IDA chemotherapy achiev- ing haematological and radiological complete remission post loid malignancy by the World Health Organisation [2], it has distinct morphological and immunophenotypic features. We cycle 1. He relapsed rapidly post a second cycle of FLAG- present two cases of BPDCN, with a visual illustration of the IDA in the short assessment period prior to reduced intensity pathological characteristics. allogenic bone marrow transplant. He failed salvage with A 69-year-old male presented with 2 months history of high-dose methotrexate and died from sepsis http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Annals of Hematology Springer Journals

Blastic plasmacytoid dendritic cell neoplasm: a pathological illustration of two clinical cases

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Hematology; Oncology
ISSN
0939-5555
eISSN
1432-0584
D.O.I.
10.1007/s00277-017-3079-6
Publisher site
See Article on Publisher Site

Abstract

Ann Hematol (2017) 96:1769–1770 DOI 10.1007/s00277-017-3079-6 LETTER TO THE EDITOR Blastic plasmacytoid dendritic cell neoplasm: a pathological illustration of two clinical cases 1 2 3 4 2,5 Jessica C. Griffin & Nayef Aqel & Wenchee Siow & Marquita Camilleri & Robert Ayto Received: 10 June 2017 /Accepted: 23 July 2017 /Published online: 1 August 2017 Springer-Verlag GmbH Germany 2017 Dear Editor, and negative for CD34, CD117, MPO and CD33, compatible Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a with BPDCN (Fig. 1, d2). Infiltrative cells on lymph node rare aggressive disease characterised by clonal proliferation of biopsy were positive for CD4, CD56 and CD123. plasmacytoid dendritic cell precursors [1]. Defined as a mye- The patient commenced FLAG-IDA chemotherapy achiev- ing haematological and radiological complete remission post loid malignancy by the World Health Organisation [2], it has distinct morphological and immunophenotypic features. We cycle 1. He relapsed rapidly post a second cycle of FLAG- present two cases of BPDCN, with a visual illustration of the IDA in the short assessment period prior to reduced intensity pathological characteristics. allogenic bone marrow transplant. He failed salvage with A 69-year-old male presented with 2 months history of high-dose methotrexate and died from sepsis

Journal

Annals of HematologySpringer Journals

Published: Aug 1, 2017

References

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