Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure

Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with... Clin Res Cardiol (2017) 106:711–721 DOI 10.1007/s00392-017-1115-0 ORIGINAL PAPER Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure 1 1 1 1 • • • • Hanna Fro ¨ hlich Lorella Torres Tobias Ta ¨ ger Dieter Schellberg 1 2 9 3 • • • • Anna Corletto Syed Kazmi Kevin Goode Morten Grundtvig 4,5 1 6,7 8 • • • • Torstein Hole Hugo A. Katus John G. F. Cleland Dan Atar 2 8 1 • • Andrew L. Clark Stefan Agewall Lutz Frankenstein Received: 24 January 2017 / Accepted: 11 April 2017 / Published online: 22 April 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract years, 302 (29.5%), 637 (37.0%), and 1232 (37.7%) Aims Beta-blockers are recommended for the treatment of patients died amongst those prescribed bisoprolol, carve- chronic heart failure (CHF). However, it is disputed whe- dilol, and metoprolol, respectively. In univariable analysis ther beta-blockers exert a class effect or whether there are of the general sample, bisoprolol and carvedilol were both differences in efficacy between agents. associated with lower mortality as compared with meto- Methods and results 6010 out-patients with stable CHF prolol succinate (HR 0.80, 95% CI 0.71–0.91, p http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Zeitschrift für Kardiologie Springer Journals

Bisoprolol compared with carvedilol and metoprolol succinate in the treatment of patients with chronic heart failure

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Cardiology
ISSN
0300-5860
eISSN
1861-0692
D.O.I.
10.1007/s00392-017-1115-0
Publisher site
See Article on Publisher Site

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