PharmacoEconomics & Outcomes News 792, p7 - 2 Dec 2017 Biologics major cost driver in IBD management in the US The increasing use of biologic therapies for the treatment of inflammatory bowel disease (IBD) has a major cost impact in the US, according to researchers from Stanford University School of Medicine, US. The researchers used data from the Truven Marketscan database to assess outpatient drug use trends of IBD medications over a 9-year period (2007–2015) and associated costs. The market share of biologics relative to other IBD medications, including immunomodulators, 5-aminosalicylic-acids (5-ASAs) and oral corticosteroids, was also determined. The analysis of data for 415 405 patients with IBD showed that the proportion of patients using biologics increased nearly threefold, from 7.1% in 2007 to 20.5% in 2015. Consequently, there was a consistent rise in the market share of biologics (from 13.7% to 30.1%) and fall for both immunomodulators and 5-ASAs (from 22.7% to 16.0% and 48.6% to 39.2%, respectively). Corticosteroid-only use remained stable at approximately 15%. The per-member per-year (PMPY) costs of an average patient receiving biologic therapy increased from $US25 275 in 2007 to $36 051 in 2015, and the share of PMPY costs for biologics increased from 72.9% to 85.7%. The study also showed that the share of PMPY costs for biologics was even higher in paediatric patients with IBD (increasing from 81.7% to 94.9%). Yu H, et al. Market share and costs of biologic therapies for inflammatory bowel disease in the USA. Alimentary Pharmacology and Therapeutics : 22 Nov 2017. Available from: URL: http://doi.org/10.1111/apt.14430 803286173 1173-5503/17/0792-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved PharmacoEconomics & Outcomes News 2 Dec 2017 No. 792
PharmacoEconomics & Outcomes News – Springer Journals
Published: Dec 2, 2017
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera