Bioinductive Scaffolds—Powerhouses of Skeletal Muscle Tissue Engineering

Bioinductive Scaffolds—Powerhouses of Skeletal Muscle Tissue Engineering Curr Pathobiol Rep (2017) 5:279–288 DOI 10.1007/s40139-017-0151-9 WOUND HEALING AND TISSUE REPAIR (CC YATES, SECTION EDITOR) Bioinductive Scaffolds—Powerhouses of Skeletal Muscle Tissue Engineering 1 2 Hari Iyer & Robert D. Galiano Published online: 14 August 2017 Springer Science+Business Media, LLC 2017 . . Abstract Keywords Skeletal muscle Volumetric muscle loss (VML) . . . Purpose of Review Skeletal muscle tissue engineering is a Mesh Polymers Biocompatible materials Extracellular . . field of vital importance to many sufferers of volumetric mus- matrix (ECM) Tissue regeneration Regenerative medicine cle loss (VML) and other muscular pathologies. Bioinductive scaffolds can host cells and modulate their behaviour and thus serve as a platform for muscle tissue growth. Introduction Recent Findings Scaffolds for skeletal muscle engineering can be composed of synthetic polymers, naturally derived The insatiable need for functional tissues throughout the spec- polymers, decellularized extracellular matrix (ECM) or any trum of medicine and disease and the imperfections of alloge- combination of these. They lead to active tissue regeneration neic organ transplantation have contributed to the enduring by modulating the initial inflammatory response, recruiting development of the field of tissue engineering. The field exists progenitor cells and determining cell phenotype. Their break- at the crossroads Current Pathobiology Reports Springer Journals

Bioinductive Scaffolds—Powerhouses of Skeletal Muscle Tissue Engineering

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Medicine & Public Health; Pathology
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