CancerMetastasisRev(2017)36:191 DOI 10.1007/s10555-017-9676-y Springer Science+Business Media, LLC 2017 Waun Ki Hong, M.D., to develop the Lung Cancer Biomarkers Core Program in the Department of Thoracic/Head and Neck Medical Oncology. Several years later, the trio would work to- gether once more to provide the infrastructure for the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination (BATTLE) trials. He was first to study the role of neurotrophins in brain cancer metastasis and to im- plement the use of CreERT conditionally targeted mice to exam- ine the role of selenium and selenoproteins in prostate cancer. More recently, Dr. Menter worked with Drs. Raymond DuBois, M.D., Ph.D., and Ernest Hawk, M.D., M.P.H, where he gained extensive experience with NSAIDs COXIBs and aspirin and colorectal cancer biology. He also developed experience with development of nanoparticle delivery vehicles for the treatment of GI cancers and the development of next-generation animal David Menter, Ph.D., is an assistant professor of Gastrointestinal models of GI cancers. He helped found ACF-Pharmaceuticals Medical Oncology at the MD Anderson Cancer Center. He LLP and serves on its executive board as a member and as chief trained with Kenneth Honn, Ph.D., and Lawrence Marnett, scientific officer. He is involved in establishing the Center Ph.D., in the study of prostaglandins in the molecular and cel- for Professional Development and Entrepreneurship as part lular biology of cancer. He published many of the early seminal of an MD Anderson program to support the innovation and papers on the role of platelets in cancer metastasis. His experi- commercialization of new technology by helping provide ence with prostaglandins and other bioactive lipids extends to a curricular offerings, collaborative networks, and profes- chapter in Prostaglandins and Cancer: The First International sional guidance. Conference, published in 1981. Drs. Honn and Menter recently Dr. Menter serves as scientific director of the Colorectal contributed to the second edition of Platelets in Thrombotic and Cancer-Moon Shot. He and Scott Kopetz, M.D., Ph.D., are Non-Thrombotic Disorders, edited by Paolo Gresele, Neal investigating the importance of colorectal cancer consensus molecular subtypes (CMS) as part of their Integromics pro- Kleiman, José Lopez, and Clive Page. Dr. Menter is an expert in the study of prostaglandins; cyclooxygenase-1 and -2; pros- gram, which utilizes and integrates next-generation sequenc- taglandin E -mediated and CSN6 signal transduction; and in- ing and other molecular data to understand the four different flammation and carcinogenesis. CMS subtypes of colorectal cancer. He also is developing Dr. Menter was awarded a National Institutes of Health post- novel mouse models to better understand the role of platelets doctoral fellowship in Human Genetics. He was then promoted in cancer and metastasis in collaboration with Anil Sood, to assistant professor and worked with Scott Lippman, M.D., to M.D., who discovered the systemic tumor-IL6: liver- establish the Department of Clinical Cancer Prevention in the thrombopoeitin: bone marrow platelet overproduction loop Division of Cancer Prevention, and then with Dr. Lippman and that drives Trousseau’ssyndrome in cancer.
Cancer and Metastasis Reviews – Springer Journals
Published: Aug 15, 2017
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