Silver nano-colloid was rapidly synthesized by treating silver ions with a blend of extracts from two leaves (Ocimum sanctum and Azadirachta indica). The reaction method was simple, eco-friendly and was monitored using UV–Vis spectroscopy. The effect of leaf extract on the formation of silver nano-colloid was studied using FTIR spectroscopy. The morphology of the synthesized colloid was stable with spherical particles of a 10-nm size. The results indicate that leaf extract acts as a reducing and stabilizing agent. The synthesized Ag nano-colloid exhibited a good colorimetric sensing property towards carcinogenic Cr(VI) anions [(Cr2O7)2−] in aqueous solution by changing the colour of the solution from “brown to red” accompanied with an increase in absorption intensity. The proposed detection method of the sensor has been discussed. The detection limit of the sensor was found to be 10−6 M. There was no interference observed for Cr(VI) anion detection in the presence of other cations and anions. The proposed sensor can be applied for the detection of Cr(VI) anion in drinking water samples. The antidiabetic ability of silver colloid was tested and the results showed inhibition of carbohydrate digestive enzymes. Thus, the current study focuses on a highly specific and selective liquid colorimetric sensor for (Cr2O7)2− anions. The silver nano-particles (Ag NPs) derived from a blend of neem (Azadirachta indica) and tulsi (Ocimum sanctum) leaves displayed an enhanced inhibitory effect towards a α-glucosidase and α-amylase enzyme model, compared to their respective crude extracts and the control. As a result, the bioderived Ag NPs can be used as new nano-therapy for the treatment of diabetes.
Research on Chemical Intermediates – Springer Journals
Published: Oct 27, 2016
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