Bevacizumab Reactions 1680, p69 - 2 Dec 2017 Endophthalmitis following an off label use: case report In a retrospective study, one patient was described [age and sex not stated], who developed endophthalmitis following an off-label treatment with bevacizumab [Avastin]. The patient was started on intravitreal bevacizumab injection PRN as an off‑label therapy for an unspecified ocular condition [dose not stated]. However, following bevacizumab administration, the patient developed endophthalmitis, which was considered to be related with bevacizumab [duration of treatment to reaction onset and outcome not stated]. Subsequently, the patient underwent vitrectomy. Author comment: "Ocular adverse drug reactions (ADRs) noted in the study group that were given injections included three patients who developed endophthalmitis". "Of the three patients with endophthalmitis, two responded to intravitreal antibiotics alone whereas one underwent vitrectomy." "The purpose of this study was to evaluate the safety profile of intravitreal bevacizumab (Avastin) as an off-label pharmacotherapeutic agent for various ocular conditions." Jain P, et al. Real-world evidence of safety profile of intravitreal bevacizumab (Avastin) in an Indian scenario. Indian Journal of Ophthalmology 65: 596-602, No. 7, Jul 2017. Available from: URL: - India 803285034 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
1 page

Loading next page...
1 Page
Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial