Cancer Causes Control (2017) 28:913–920 DOI 10.1007/s10552-017-0918-7 OR IGINAL PAPER 1 2 3 4 • • • • Juhua Luo Michael Hendryx Rami Nassir Ting-Yuan David Cheng 5 6 Dorothy Lane Karen L. Margolis Received: 31 March 2017 / Accepted: 21 June 2017 / Published online: 6 July 2017 Springer International Publishing AG 2017 Abstract There were no signiﬁcant differences in thyroid tumor size, Background It has been suggested that breast and thyroid stage or histologic types between women with and without diseases may be linked. The aim of this study was to BBD. investigate the association between benign breast disease Conclusion Our large prospective study observed that and subsequent risk of thyroid cancer. postmenopausal women with BBD had an increased risk Methods Postmenopausal women (n = 133,875) aged for thyroid cancer compared with women without BBD. A 50–79 years were followed up for a mean of 14 years. more detailed investigation of thyroid cancer risk accord- Benign breast disease was deﬁned by history of biopsy. ing to different subtypes of benign breast disease is needed Incident thyroid cancer cases were conﬁrmed by medical to better understand the association observed between record review. Multivariable Cox proportional hazard thyroid and
Cancer Causes & Control – Springer Journals
Published: Jul 6, 2017
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