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A. Mungall, S. Palmer, S. Sims, C. Edwards, J. Ashurst, L. Wilming, M. Jones, R. Horton, S. Hunt, C. Scott, J. Gilbert, M. Clamp, G. Bethel, S. Milne, R. Ainscough, J. Almeida, K. Ambrose, T. Andrews, R. Ashwell, A. Babbage, C. Bagguley, J. Bailey, R. Banerjee, D. Barker, K. Barlow, K. Bates, D. Beare, H. Beasley, O. Beasley, C. Bird, S. Blakey, S. Bray-Allen, J. Brook, A. Brown, J. Brown, D. Burford, W. Burrill, J. Burton, C. Carder, N. Carter, J. Chapman, S. Clark, G. Clark, C. Clee, S. Clegg, V. Cobley, R. Collier, J. Collins, L. Colman, N. Corby, G. Coville, K. Culley, P. Dhami, J. Davies, M. Dunn, M. Earthrowl, A. Ellington, K. Evans, L. Faulkner, M. Francis, A. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, M. Ghori, L. Gilby, C. Gillson, R. Glithero, D. Grafham, M. Grant, S. Gribble, C. Griffiths, M. Griffiths, R. Hall, K. Halls, S. Hammond, J. Harley, E. Hart, P. Heath, R. Heathcott, S. Holmes, P. Howden, K. Howe, G. Howell, E. Huckle, S. Humphray, M. Humphries, A. Hunt, C. Johnson, A. Joy, M. Kay, S. Keenan, A. Kimberley, A. King, G. Laird, C. Langford, S. Lawlor, D. Leongamornlert, M. Leversha, C. Lloyd, D. Lloyd, J. Loveland, J. Lovell, S. Martin, M. Mashreghi-mohammadi, G. Maslen, L. Matthews, O. Mccann, S. McLaren, K. McLay, A. McMurray, M. Moore, J. Mullikin, D. Niblett, T. Nickerson, K. Novik, K. Oliver, E. Overton-Larty, A. Parker, R. Patel, A. Pearce, A. Peck, B. Phillimore, S. Phillips, R. Plumb, K. Porter, Y. Ramsey, S. Ranby, C. Rice, M. Ross, S. Searle, H. Sehra, E. Sheridan, C. Skuce, S. Smith, M. Smith, L. Spraggon, S. Squares, C. Steward, N. Sycamore, G. Tamlyn-Hall, J. Tester, A. Theaker, D. Thomas, A. Thorpe, A. Tracey, A. Tromans, B. Tubby, M. Wall, J. Wallis, A. West, S. White, S. Whitehead, H. Whittaker, A. Wild, D. Willey, T. Wilmer, J. Wood, P. Wray, J. Wyatt, L. Young, R. Younger, D. Bentley, A. Coulson, R. Durbin, T. Hubbard, J. Sulston, I. Dunham, J. Rogers, S. Beck (2003)
The DNA sequence and analysis of human chromosome 6Nature, 425
P. Rice, Ian Longden, A. Bleasby (2000)
EMBOSS: the European Molecular Biology Open Software Suite.Trends in genetics : TIG, 16 6
David Gordon, C. Abajian, P. Green (1998)
Consed: a graphical tool for sequence finishing.Genome research, 8 3
Brent Ewing, Philip Green (1998)
Base-calling of automated sequencer traces using phred. II. Error probabilities.Genome research, 8 3
A. Mungall, S. Palmer, S. Sims, C. Edwards, J. Ashurst, L. Wilming, M. Jones, R. Horton, S. Hunt, C. Scott, J. Gilbert, M. Clamp, G. Bethel, S. Milne, R. Ainscough, J. Almeida, K. Ambrose, T. Andrews, R. Ashwell, A. Babbage, C. Bagguley, J. Bailey, R. Banerjee, Darren Barker, K. Barlow, K. Bates, D. Beare, H. Beasley, O. Beasley, C. Bird, S. Blakey, S. Bray-Allen, J. Brook, A. Brown, J. Brown, D. Burford, W. Burrill, J. Burton, C. Carder, N. Carter, J. Chapman, S. Clark, G. Clark, C. Clee, S. Clegg, V. Cobley, R. Collier, J. Collins, L. Colman, N. Corby, G. Coville, K. Culley, P. Dhami, J. Davies, M. Dunn, M. Earthrowl, A. Ellington, K. Evans, L. Faulkner, M. Francis, A. Frankish, J. Frankland, L. French, P. Garner, J. Garnett, Mohammed Ghori, L. Gilby, C. Gillson, R. Glithero, D. Grafham, M. Grant, S. Gribble, C. Griffiths, M. Griffiths, R. Hall, K. Halls, S. Hammond, J. Harley, E. Hart, P. Heath, R. Heathcott, S. Holmes, P. Howden, K. Howe, Gareth Howell, E. Huckle, S. Humphray, M. Humphries, A. Hunt, C. Johnson, A. Joy, M. Kay, S. Keenan, A. Kimberley, A. King, G. Laird, C. Langford, S. Lawlor, D. Leongamornlert, M. Leversha, C. Lloyd, D. Lloyd, J. Loveland, J. Lovell, S. Martin, M. Mashreghi-mohammadi, G. Maslen, L. Matthews, O. Mccann, S. McLaren, K. McLay, A. McMurray, M. Moore, J. Mullikin, D. Niblett, T. Nickerson, K. Novik, K. Oliver, E. Overton-Larty, Anne Parker, R. Patel, A. Pearce, A. Peck, B. Phillimore, S. Phillips, R. Plumb, K. Porter, Y. Ramsey, S. Ranby, C. Rice, M. Ross, S. Searle, H. Sehra, E. Sheridan, C. Skuce, Sarah Smith, M. Smith, L. Spraggon, S. Squares, C. Steward, N. Sycamore, G. Tamlyn-Hall, J. Tester, A. Theaker, D. Thomas, A. Thorpe, A. Tracey, A. Tromans, B. Tubby, M. Wall, J. Wallis, A. West, S. White, S. Whitehead, H. Whittaker, A. Wild, D. Willey, T. Wilmer, J. Wood, P. Wray, J. Wyatt, L. Young, R. Younger, D. Bentley, A. Coulson, R. Durbin, T. Hubbard, J. Sulston, I. Dunham, J. Rogers, Stephan Beck (2003)
DNA sequence and analysis of human chromosome 9Nature, 429
B. Hayward, Verónica Morán, L. Strain, D. Bonthron (1998)
Bidirectional imprinting of a single gene: GNAS1 encodes maternally, paternally, and biallelically derived proteins.Proceedings of the National Academy of Sciences of the United States of America, 95 26
K. Kosaki, R. Kosaki, W. Craigen, N. Matsuo (2000)
Isoform-specific imprinting of the human PEG1/MEST gene.American journal of human genetics, 66 1
Aleksey Yevtodiyenko, M. Carr, N. Patel, Jennifer Schmidt (2002)
Analysis of candidate imprinted genes linked to Dlk1-Gtl2 using a congenic mouse lineMammalian Genome, 13
Erica Davis, C. Jensen, H. Schrøder, F. Farnir, Tracy Shay-Hadfield, A. Kliem, N. Cockett, M. Georges, C. Charlier (2004)
Ectopic Expression of DLK1 Protein in Skeletal Muscle of Padumnal Heterozygotes Causes the Callipyge PhenotypeCurrent Biology, 14
P. Georgiades, M. Watkins, M. Surani, A. Ferguson-Smith (2000)
Parental origin-specific developmental defects in mice with uniparental disomy for chromosome 12.Development, 127 21
(1998)
de - fects in mice with uniparental disomy for chromosome 12
Roland Bunzel, Ingmar Blümcke, S. Cichon, S. Normann, Johannes Schramm, P. Propping, M. Nöthen (1998)
Polymorphic imprinting of the serotonin-2A (5-HT2A) receptor gene in human adult brain.Brain research. Molecular brain research, 59 1
Jennifer Schmidt, Paul Matteson, Beverly Jones, Xiao Guan, S. Tilghman (2000)
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted.Genes & development, 14 16
Shau-Ping Lin, N. Youngson, S. Takada, H. Seitz, W. Reik, M. Paulsen, J. Cavaille, A. Ferguson-Smith (2003)
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12Nature Genetics, 35
Erica Davis, F. Caiment, X. Tordoir, J. Cavaille, A. Ferguson-Smith, N. Cockett, M. Georges, C. Charlier (2005)
RNAi-Mediated Allelic trans-Interaction at the Imprinted Rtl1/Peg11 LocusCurrent Biology, 15
I. Yao, Junko Iida, W. Nishimura, Y. Hata (2002)
Synaptic and Nuclear Localization of Brain-Enriched Guanylate Kinase-Associated ProteinThe Journal of Neuroscience, 22
Takashi Sakatani, Michelle Wei, M. Katoh, Chiga Okita, Daisuke Wada, K. Mitsuya, M. Meguro, M. Ikeguchi, Hisao Ito, Benjamin Tycko, Mitsuo Oshimura (2001)
Epigenetic heterogeneity at imprinted loci in normal populations.Biochemical and biophysical research communications, 283 5
R. Waterston, K. Lindblad-Toh, E. Birney, J. Rogers, J. Abril, P. Agarwal, R. Agarwala, R. Ainscough, M. Alexandersson, Peter An, S. Antonarakis, J. Attwood, R. Baertsch, J. Bailey, K. Barlow, S. Beck, E. Berry, B. Birren, Toby Bloom, P. Bork, M. Botcherby, Nicolas Bray, M. Brent, Daniel Brown, Stephen Brown, C. Bult, J. Burton, Jonathan Butler, R. Campbell, Piero Carninci, S. Cawley, F. Chiaromonte, A. Chinwalla, D. Church, M. Clamp, C. Clee, F. Collins, L. Cook, R. Copley, A. Coulson, O. Couronne, James Cuff, V. Curwen, T. Cutts, M. Daly, R. David, J. Davies, K. Delehaunty, J. Deri, E. Dermitzakis, Colin Dewey, N. Dickens, M. Diekhans, S. Dodge, I. Dubchak, D. Dunn, S. Eddy, L. Elnitski, Richard Emes, P. Eswara, E. Eyras, A. Felsenfeld, G. Fewell, P. Flicek, Karen Foley, W. Frankel, L. Fulton, R. Fulton, T. Furey, D. Gage, R. Gibbs, Gwênlyn Glusman, S. Gnerre, N. Goldman, L. Goodstadt, D. Grafham, T. Graves, E. Green, S. Gregory, R. Guigó, M. Guyer, R. Hardison, D. Haussler, Y. Hayashizaki, Deana LaHillier, A. Hinrichs, W. Hlavina, T. Holzer, F. Hsu, A. Hua, T. Hubbard, A. Hunt, I. Jackson, D. Jaffe, L. Johnson, Matthew Jones, T. Jones, A. Joy, Michael Kamal, E. Karlsson, D. Karolchik, A. Kasprzyk, J. Kawai, Evan Keibler, C. Kells, W. Kent, Andrew Kirby, D. Kolbe, I. Korf, R. Kucherlapati, E. Kulbokas, D. Kulp, Tom Landers, J. Leger, Steven Leonard, Ivica Letunic, R. Levine, Jia Li, Ming Li, C. Lloyd, S. Lucas, Bin Ma, D. Maglott, E. Mardis, L. Matthews, E. Mauceli, John Mayer, M. McCarthy, W. McCombie, Stuart Mclaren, K. McLay, J. McPherson, J. Meldrim, B. Meredith, J. Mesirov, W. Miller, T. Miner, Emmanuel Mongin, K. Montgomery, M. Morgan, R. Mott, J. Mullikin, D. Muzny, W. Nash, J. Nelson, M. Nhan, R. Nicol, Z. Ning, C. Nusbaum, M. O’Connor, Y. Okazaki, K. Oliver, E. Overton-Larty, L. Pachter, Genís Parra, K. Pepin, Jane Peterson, P. Pevzner, R. Plumb, C. Pohl, Alexander Poliakov, Tracy Ponce, C. Ponting, Simon Potter, M. Quail, A. Reymond, B. Roe, K. Roskin, E. Rubin, A. Rust, R. Santos, V. Sapojnikov, Brian Schultz, J. Schultz, M. Schwartz, S. Schwartz, C. Scott, S. Seaman, S. Searle, Ted Sharpe, A. Sheridan, R. Shownkeen, S. Sims, J. Singer, G. Slater, A. Smit, Douglas Smith, B. Spencer, Arne Stabenau, N. Stange-thomann, C. Sugnet, M. Suyama, G. Tesler, J. Thompson, D. Torrents, E. Trevaskis, J. Tromp, C. Ucla, A. Ureta-Vidal, J. Vinson, A. Niederhausern, C. Wade, M. Wall, R. Weber, R. Weiss, M. Wendl, A. West, K. Wetterstrand, R. Wheeler, S. Whelan, Jamey Wierzbowski, D. Willey, Sophie Williams, R. Wilson, E. Winter, K. Worley, D. Wyman, Shan Yang, Shiaw-Pyng Yang, E. Zdobnov, M. Zody, E. Lander (2002)
Initial sequencing and comparative analysis of the mouse genome.Nature, 420
W. Rychlik, R. Rhoads (1989)
A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA.Nucleic acids research, 17 21
R. Heilig, R. Eckenberg, Jean‐Louis Petit, N. Fonknechten, Corinne Silva, L. Cattolico, M. Levy, V. Barbe, V. Berardinis, A. Ureta-Vidal, É. Pelletier, V. Vico, Véronique Anthouard, L. Rowen, A. Madan, S. Qin, Hui Sun, H. Du, K. Pepin, F. Artiguenave, C. Robert, C. Cruaud, T. Brüls, O. Jaillon, L. Friedlander, Gaelle Samson, P. Brottier, S. Cure, Béatrice Segurens, Franck Anière, S. Samain, H. Crespeau, N. Abbasi, N. Aiach, D. Boscus, Rachel Dickhoff, Monica Dors, Ivan Dubois, C. Friedman, M. Gouyvenoux, R. James, A. Madan, Barbara Mairey–Estrada, S. Mangenot, Nathalie Martins, M. Ménard, S. Oztas, A. Ratcliffe, T. Shaffer, B. Trask, B. Vacherie, C. Bellemere, Caroline Belser, Marielle Besnard-Gonnet, Delphine Bartol–Mavel, Magali Boutard, Stéphanie Briez-Silla, Stephane Combette, Virginie Dufossé-Laurent, Carolyne Ferron, Christophe Lechaplais, Claudine Louesse, D. Muselet, Ghislaine Magdelenat, Emilie Pateau, E. Petit, Peggy Sirvain-Trukniewicz, Arnaud Trybou, N. Vega-Czarny, Elodie Bataille, Elodie Bluet, I. Bordelais, M. Dubois, C. Dumont, Thomas Guérin, Sébastien Haffray, Rachid Hammadi, Jacqueline Muanga, Virginie Pellouin, D. Robert, E. Wunderle, Gilbert Gauguet, A. Roy, Laurent Sainte-Marthe, Jean-Émile Verdier, Claude Verdier-Discala, L. Hillier, L. Fulton, J. McPherson, F. Matsuda, R. Wilson, C. Scarpelli, G. Gyapay, P. Wincker, W. Saurin, F. Quétier, R. Waterston, L. Hood, J. Weissenbach (2023)
The DNA sequence and analysis of human chromosome 14Nature, 421
J. Greally (2001)
Short interspersed transposable elements (SINEs) are excluded from imprinted regions in the human genomeProceedings of the National Academy of Sciences of the United States of America, 99
T. Vu, A. Hoffman (1994)
Promoter-specific imprinting of the human insulin-like growth factor-II geneNature, 371
N. Cockett, S. Jackson, T. Shay, F. Farnir, S. Berghmans, G. Snowder, D. Nielsen, M. Georges (1996)
Polar Overdominance at the Ovine callipyge LocusScience, 273
(2005)
RNAi-mediated allelic trans-interaction at the imprinted callipyge locus
A. Fanning, James Anderson (1999)
Protein modules as organizers of membrane structure.Current opinion in cell biology, 11 4
(2000)
Parental origin - specific
C. Chu, S. Schwartz, E. McPherson (2004)
Paternal uniparental isodisomy for chromosome 14 in a patient with a normal 46,XY karyotypeAmerican Journal of Medical Genetics Part A, 127A
J. Cavaille, H. Seitz, M. Paulsen, A. Ferguson-Smith, J. Bachellerie (2002)
Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region.Human molecular genetics, 11 13
M. Georges, C. Charlier, N. Cockett (2003)
The callipyge locus: evidence for the trans interaction of reciprocally imprinted genes.Trends in genetics : TIG, 19 5
Y. Jinno, Md. Hasan, K. Nishiwaki, T. Kubota, O. Ogawa, A. Reeve, N. Niikawa (1994)
Mosaic and polymorphic imprinting of the WT1 gene in humansNature Genetics, 6
Andrew Wylie, Susan Murphy, Terry Orton, R. Jirtle (2000)
Novel imprinted DLK1/GTL2 domain on human chromosome 14 contains motifs that mimic those implicated in IGF2/H19 regulation.Genome research, 10 11
Y. Xu, C. Goodyer, C. Deal, C. Polychronakos (1993)
Functional polymorphism in the parental imprinting of the human IGF2R gene.Biochemical and biophysical research communications, 197 2
C. Bidwell, T. Shay, M. Georges, J. Beever, S. Berghmans, N. Cockett (2001)
Differential expression of the GTL2 gene within the callipyge region of ovine chromosome 18.Animal genetics, 32 5
(2003)
Access the most recent version at doi: 10.1101/gr.926603 References
E. Birney, T. Andrews, Paul Bevan, M. Cáccamo, G. Cameron, Yuan Chen, Laura Clarke, Guy Coates, Tony Cox, James Cuff, V. Curwen, T. Cutts, T. Down, R. Durbin, E. Eyras, X. Fernández-Suárez, P. Gane, B. Gibbins, J. Gilbert, M. Hammond, H. Hotz, V. Iyer, Andreas Kähäri, K. Jekosch, A. Kasprzyk, Damian Keefe, S. Keenan, H. Lehväslaiho, G. McVicker, Craig Melsopp, P. Meidl, Emmanuel Mongin, Roger Pettett, Simon Potter, G. Proctor, Mark Rae, S. Searle, G. Slater, D. Smedley, James Smith, W. Spooner, Arne Stabenau, J. Stalker, R. Storey, A. Ureta-Vidal, Cara Woodwark, M. Clamp, T. Hubbard (2004)
Ensembl 2004Nucleic acids research, 32 Database issue
H. Seitz, N. Youngson, Shau-Ping Lin, Simone Dalbert, M. Paulsen, J. Bachellerie, A. Ferguson-Smith, J. Cavaille (2003)
Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like geneNature Genetics, 34
D. Sanlaville, M. Aubry, Y. Dumez, M. Nolen, J. Amiel, M. Pinson, S. Lyonnet, A. Munnich, M. Vekemans, N. Morichon‐Delvallez (2000)
Maternal uniparental heterodisomy of chromosome 14: chromosomal mechanism and clinical follow upJournal of Medical Genetics, 37
(2003)
MRC Mammalian Genetics Unit, Harwell, Oxfordshire. Mouse Imprinting Data and References available at http://www.mgu.har.mrc.ac.uk/imprinting/ imprinting/html
L. Weinstein, Shuhua Yu, C. Ecelbarger (2000)
Variable imprinting of the heterotrimeric G protein Gsα-subunit within different segments of the nephronAmerican Journal of Physiology-renal Physiology, 278
C. Charlier, K. Segers, L. Karim, T. Shay, G. Gyapay, N. Cockett, M. Georges (2001)
The callipyge mutation enhances the expression of coregulated imprinted genes in cis without affecting their imprinting statusNature Genetics, 27
C. Charlier, Karin Segers, Danny Wagenaar, L. Karim, Stéphane Berghmans, O. Jaillon, Tracy Shay, Jean Weissenbach, N. Cockett, Gabor Gyapay, Michel Georges (2001)
Human-ovine comparative sequencing of a 250-kb imprinted domain encompassing the callipyge (clpg) locus and identification of six imprinted transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8.Genome research, 11 5
Nadya Blagitko, S. Mergenthaler, U. Schulz, Hartmut Wollmann, William Craigen, Thomas Eggermann, H. Ropers, V. Kalscheuer (2000)
Human GRB10 is imprinted and expressed from the paternal and maternal allele in a highly tissue- and isoform-specific fashion.Human molecular genetics, 9 11
S. Takada, M. Paulsen, M. Tevendale, Chen-en Tsai, G. Kelsey, B. Cattanach, A. Ferguson-Smith (2002)
Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19.Human molecular genetics, 11 1
M. Sheng (2001)
Molecular organization of the postsynaptic specializationProceedings of the National Academy of Sciences of the United States of America, 98
Shuji Takada, M. Tevendale, J. Baker, Pantelis Georgiades, Elizabeth Campbell, Tom Freeman, Martin Johnson, Martina Paulsen, A. Ferguson-Smith (2000)
Delta-like and Gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12Current Biology, 10
H. Seitz, Hélène Royo, M. Bortolin, Shau-Ping Lin, A. Ferguson-Smith, J. Cavaille (2004)
A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain.Genome research, 14 9
R. Verona, M. Mann, M. Bartolomei (2003)
Genomic imprinting: intricacies of epigenetic regulation in clusters.Annual review of cell and developmental biology, 19
H. Uejima, M. Lee, H. Cui, A. Feinberg (2000)
Hot-stop PCR: a simple and general assay for linear quantitation of allele ratiosNature Genetics, 25
K. Segers, Daniel Vaiman, S. Berghmans, T. Shay, S. Meyers, J. Beever, N. Cockett, M. Georges, C. Charlier (2000)
Construction and characterization of an ovine BAC contig spanning the callipyge locus.Animal genetics, 31 6
M. Rebhan, V. Chalifa-Caspi, J. Prilusky, D. Lancet (1997)
GeneCards: integrating information about genes, proteins and diseases.Trends in genetics : TIG, 13 4
Y. Hata, Y. Takai (1999)
Roles of postsynaptic density-95/synapse-associated protein 90 and its interacting proteins in the organization of synapsesCellular and Molecular Life Sciences CMLS, 56
L. Weinstein (2001)
The role of tissue-specific imprinting as a source of phenotypic heterogeneity in human diseaseBiological Psychiatry, 50
B. Modrek, Christopher Lee (2002)
A genomic view of alternative splicingNature Genetics, 30
R. Lyle, D. Watanabe, D. Vruchte, W. Lerchner, O. Smrzka, A. Wutz, J. Schageman, L. Hahner, Christopher Davies, D. Barlow (2000)
The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1Nature Genetics, 25
D. Barlow (1995)
Gametic Imprinting in MammalsScience, 270
M Brudno, CB Do, GM Cooper, MF Kim, E Davydov (2003)
LAGAN and Multi-LAGAN: Efficient tools for large-scale multiple alignment of genomic DNAGenome Res, 13
D Vaiman, A Billault, K Tabet-Aoul, L Schibler, D Vilette (1999)
Construction and characterization of a sheep BAC library of three genome equivalentsMamm Genome, 10
J. Jurka (2000)
Repbase update: a database and an electronic journal of repetitive elements.Trends in genetics : TIG, 16 9
Chen-en Tsai, Shau-Ping Lin, Mitsuteru Ito, N. Takagi, S. Takada, A. Ferguson-Smith (2002)
Genomic Imprinting Contributes to Thyroid Hormone Metabolism in the Mouse EmbryoCurrent Biology, 12
Article Identification and Characterization of Multi-Species Conserved Sequences
Arturo Hernandez, S. Fiering, Elena Martinez, V. Galton, D. Germain (2002)
The gene locus encoding iodothyronine deiodinase type 3 (Dio3) is imprinted in the fetus and expresses antisense transcripts.Endocrinology, 143 11
Bland Ewing, L. Hillier, M. Wendl, Philip Green (1998)
Base-calling of automated sequencer traces using phred. I. Accuracy assessment.Genome research, 8 3
B. Freking, S. Murphy, A. Wylie, S. Rhodes, J. Keele, K. Leymaster, R. Jirtle, T. Smith (2002)
Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals.Genome research, 12 10
M. Deguchi, Y. Hata, M. Takeuchi, N. Ide, K. Hirao, I. Yao, M. Irie, A. Toyoda, Y. Takai (1998)
BEGAIN (Brain-enriched Guanylate Kinase-associated Protein), a Novel Neuronal PSD-95/SAP90-binding Protein*The Journal of Biological Chemistry, 273
M. Smit, K. Segers, L. Carrascosa, T. Shay, F. Baraldi, G. Gyapay, G. Snowder, M. Georges, N. Cockett, C. Charlier (2003)
Mosaicism of Solid Gold supports the causality of a noncoding A-to-G transition in the determinism of the callipyge phenotype.Genetics, 163 1
M. Gardiner-Garden, M. Frommer1v, ‘The Kanematsu (1987)
CpG islands in vertebrate genomes.Journal of molecular biology, 196 2
N. Miyoshi, H. Wagatsuma, S. Wakana, T. Shiroishi, Masashi Nomura, K. Aisaka, T. Kohda, M. Surani, T. Kaneko-Ishino, F. Ishino (2000)
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14qGenes to Cells, 5
S. Kobayashi, H. Wagatsuma, R. Ono, H. Ichikawa, M. Yamazaki, H. Tashiro, K. Aisaka, N. Miyoshi, T. Kohda, A. Ogura, M. Ohki, T. Kaneko-Ishino, F. Ishino (2000)
Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse Meg3/Gtl2 and human MEG3Genes to Cells, 5
In this article we describe the organization of the ovine BEGAIN gene, located 138 kb proximally from the imprinted DLK1 gene and 203 kb from the CLPG mutation that causes the callipyge phenotype. We have shown that in sheep BEGAIN is ubiquitously expressed, including in skeletal muscle, throughout development. We have identified four major BEGAIN transcripts resulting from a combination of alternate promoter usage and alternative splicing. In ovine brain, kidney, liver, and skeletal muscle, these four BEGAIN transcripts exhibited paternal or biallelic expression in a tissue- and promoter-specific manner. Our results indicate that the CLPG mutation does not alter transcript levels of BEGAIN, contrary to its effect on a core cluster of genes in the DLK1-GTL2 domain. Thus, although the BEGAIN gene represents another paternally expressed gene in the ovine DLK1-GTL2 imprinted domain, its expression is not governed by the long-range regulatory element that contains the CLPG mutation.
Mammalian Genome – Springer Journals
Published: Oct 29, 2005
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