OBES SURG (2017) 27:3156–3164 DOI 10.1007/s11695-017-2737-z ORIGINAL CONTRIBUTIONS Bariatric Surgery-Induced Resolution of Hypertension and Obstructive Sleep Apnea: Impact of Modulation of Body Fat, Ectopic Fat, Autonomic Nervous Activity, Inflammatory and Adipokine Profiles 1,2 1,3 1,3 1,3 Audrey Auclair & Laurent Biertho & Simon Marceau & Frédéric-Simon Hould & 1,3 1,3 1,3 1,3 Simon Biron & Stéfane Lebel & François Julien & Odette Lescelleur & 1 1,3 1 4 Yves Lacasse & Marie-Eve Piché & Katherine Cianflone & Sebastian Demian Parlee & 5,6 1,2 1,2 7 Kerry Goralski & Julie Martin & Marjorie Bastien & David H. St-Pierre & 1,2 Paul Poirier Published online: 29 May 2017 Springer Science+Business Media New York 2017 Abstract tomography scan, and 24-h heart rate monitoring were per- Background Obesity-associated systemic hypertension (HTN) formed. OSA have been determined with polysomnography and obstructive sleep apnea (OSA) have multiple pathophysio- and HTN with blood pressure measurement and medical file. logical pathways including ectopic fat deposition, inflammation, Results Patients with HTN (n=35)andOSA(n = 32) were older altered adipokine profile, and increased sympathetic nervous ac- men with higher ectopic fat deposition and lower parasympathet- tivity. We characterized these potential mechanisms in severely ic nervous activity without difference in adipokines
Obesity Surgery – Springer Journals
Published: May 29, 2017
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