Baclofen overdose

Baclofen overdose Reactions 1704, p64 - 2 Jun 2018 O S Various toxicities: case report A 27-year-old man developed unresponsive state, respiratory failure after an attempted suicide following baclofen intoxication [time to reaction onsets not stated]. The man was admitted to the emergency department after he was found in an unresponsive state. He had attempted suicide by taking 850mg of baclofen, 2.5 litres of beer and heroine. After heteroanamnesis, he was diagnosed with baclofen intoxication. He developed respiratory failure and was intubated. He received treatment with a laxative, activated charcoal and other drugs to avoid withdrawal symptoms. Subsequently, his condition improved and he was extubated 60 hours after admission. Author comment: "After heteroanamnesis, he was diagnosed with an intoxication of 850 mg baclofen, 2.5 liters’ beer and an unknown amount of heroine." Mitrovic D, et al. Course and treatment of baclofen intoxication. [Dutch]. Pharmaceutisch Weekblad 153: 13-16, No. 14, 6 Apr 2018 [Dutch; summarised from an English abstract] - Netherlands 803323467 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Baclofen overdose

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
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Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46707-x
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p64 - 2 Jun 2018 O S Various toxicities: case report A 27-year-old man developed unresponsive state, respiratory failure after an attempted suicide following baclofen intoxication [time to reaction onsets not stated]. The man was admitted to the emergency department after he was found in an unresponsive state. He had attempted suicide by taking 850mg of baclofen, 2.5 litres of beer and heroine. After heteroanamnesis, he was diagnosed with baclofen intoxication. He developed respiratory failure and was intubated. He received treatment with a laxative, activated charcoal and other drugs to avoid withdrawal symptoms. Subsequently, his condition improved and he was extubated 60 hours after admission. Author comment: "After heteroanamnesis, he was diagnosed with an intoxication of 850 mg baclofen, 2.5 liters’ beer and an unknown amount of heroine." Mitrovic D, et al. Course and treatment of baclofen intoxication. [Dutch]. Pharmaceutisch Weekblad 153: 13-16, No. 14, 6 Apr 2018 [Dutch; summarised from an English abstract] - Netherlands 803323467 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

References

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