Reactions 1704, p61 - 2 Jun 2018 Oral bullous lesions: case report A 29-year-old woman developed oral bullous lesions following treatment with azithromycin [Sumamed] for pneumonia. The woman was hospitalised and a clinical examination showed red eyes and two bullae located on the right buccal mucosa. A day prior to the admission, she had completed azithromycin therapy. She had been receiving oral azithromycin 500mg tablet per day for three days for pneumonia. A biopsy specimen of the buccal mucosa was examined. Indirect immunofluoroscence examination did not show circulating antibodies of pemphigus or bullous pemphigoid. These findings excluded diagnosis of an autoimmune blistering disease. Her eyes were red probably due to allergy like a mild Stevens-Johnson syndrome. She was diagnosed with oral bullous lesions. The woman was treated with prednisone and betamethasone. Nine days later, her lesions improved and at three months follow-up, her lesions had completely disappeared. Author comment: "To our knowledge this is the second case upon solely oral reaction to azithromycin in the so far published literature. We reported first case upon oral bullous reaction due to the azithromycin in the year 2011." Boras VV, et al. Oral bullous lesions due to the azithromycin intake. Australasian Medical Journal 11: 237-239, No. 4, Jan 2018. Available from: URL: http:// doi.org/10.21767/AMJ.2018.3388 - Croatia 803322940 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704
Reactions Weekly – Springer Journals
Published: Jun 2, 2018
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