Autoimmune cerebellar ataxia with glutamic acid decarboxylase 65 antibodies associated with central vestibular symptoms

Autoimmune cerebellar ataxia with glutamic acid decarboxylase 65 antibodies associated with... Acta Neurol Belg (2017) 117:775–776 DOI 10.1007/s13760-016-0733-z LETTER TO THE EDITOR Autoimmune cerebellar ataxia with glutamic acid decarboxylase 65 antibodies associated with central vestibular symptoms 1 1 1,2 1,3 • • • • Fre ´de ´ric London Nawal Hadhoum He ´le `ne Ze ´phir Olivier Outteryck 1,4 Patrick Vermersch Received: 8 October 2016 / Accepted: 2 December 2016 / Published online: 17 December 2016 Belgian Neurological Society 2016 Keywords Glutamic acid decarboxylase  Autoimmunity  Case presentation Central vestibular pathway A 40-year-old man with medical history of insulin-depen- dant type 1 diabetes mellitus (DM1) since 5 years com- Introduction plained in 2014 of subacute onset of mild but constant vertigo increasing with head movements, especially to the The spectrum of neurological syndromes associated with right. He had no hearing loss but reported mild nausea. antibodies to glutamic acid decarboxylase 65 (GAD65-Ab) Clinical examination performed by otolaryngologist includes cerebellar ataxia (CA), stiff-person syndrome, demonstrated harmonious vestibular syndrome since limbic encephalitis, progressive encephalomyelitis, and videonystagmography showed positional nystagmus drift- some refractory epileptic patients [1]. We describe a ing toward the right side, Dix Hallpike test was positive patient presenting with central vestibular symptoms pre- and otolithic evoked potentials showed decreased sacculo- http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Acta Neurologica Belgica Springer Journals

Autoimmune cerebellar ataxia with glutamic acid decarboxylase 65 antibodies associated with central vestibular symptoms

Loading next page...
 
/lp/springer_journal/autoimmune-cerebellar-ataxia-with-glutamic-acid-decarboxylase-65-5r5IOk59Sf
Publisher
Springer International Publishing
Copyright
Copyright © 2016 by Belgian Neurological Society
Subject
Biomedicine; Neurosciences; Neurology; Neuroradiology; Medicine/Public Health, general
ISSN
0300-9009
eISSN
2240-2993
D.O.I.
10.1007/s13760-016-0733-z
Publisher site
See Article on Publisher Site

Abstract

Acta Neurol Belg (2017) 117:775–776 DOI 10.1007/s13760-016-0733-z LETTER TO THE EDITOR Autoimmune cerebellar ataxia with glutamic acid decarboxylase 65 antibodies associated with central vestibular symptoms 1 1 1,2 1,3 • • • • Fre ´de ´ric London Nawal Hadhoum He ´le `ne Ze ´phir Olivier Outteryck 1,4 Patrick Vermersch Received: 8 October 2016 / Accepted: 2 December 2016 / Published online: 17 December 2016 Belgian Neurological Society 2016 Keywords Glutamic acid decarboxylase  Autoimmunity  Case presentation Central vestibular pathway A 40-year-old man with medical history of insulin-depen- dant type 1 diabetes mellitus (DM1) since 5 years com- Introduction plained in 2014 of subacute onset of mild but constant vertigo increasing with head movements, especially to the The spectrum of neurological syndromes associated with right. He had no hearing loss but reported mild nausea. antibodies to glutamic acid decarboxylase 65 (GAD65-Ab) Clinical examination performed by otolaryngologist includes cerebellar ataxia (CA), stiff-person syndrome, demonstrated harmonious vestibular syndrome since limbic encephalitis, progressive encephalomyelitis, and videonystagmography showed positional nystagmus drift- some refractory epileptic patients [1]. We describe a ing toward the right side, Dix Hallpike test was positive patient presenting with central vestibular symptoms pre- and otolithic evoked potentials showed decreased sacculo-

Journal

Acta Neurologica BelgicaSpringer Journals

Published: Dec 17, 2016

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off