Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific

Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific Diabetologia (2017) 60:1834–1835 DOI 10.1007/s00125-017-4376-2 RESEARCH LETTER Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific 1 2 1 3 Ilaria Marzinotto & Daniela Liberati & Cristina Brigatti & Riccardo Bonfanti & 1 1 1,4 1,4 Angela Stabilini & Paolo Monti & Emanuele Bosi & Lorenzo Piemonti & Vito Lampasona Received: 30 May 2017 /Accepted: 13 June 2017 /Published online: 19 July 2017 Springer-Verlag GmbH Germany 2017 . . . . Keywords Autoantibodies Autoimmunity ELISA IL-2 locyte colony-stimulating factor, IL-6, IL-17 and IL-22, have . . Immunoprecipitation LIPS Type 1 diabetes been described in a variety of other diseases, including auto- immune syndromes sometimes presenting together with type 1 diabetes [2]. In an original report by Pérol et al [1], IL-2 auto- antibodies, measured by a direct ELISA assay, were suggested to be present in the NOD mouse, where they correlated with Abbreviations disease development, and in around 25% of humans at onset of LIPS Luciferase immunoprecipitation system type 1 diabetes. To investigate the presence of IL-2 autoanti- NLuc-IL-2 Recombinant IL-2 tagged with a NanoLuc bodies in human type 1 diabetes, we developed a novel assay luciferase reporter based on the luciferase http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetologia Springer Journals

Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific

Loading next page...
1
 
/lp/springer_journal/autoantibody-binding-in-liquid-phase-to-il-2-in-human-sera-is-not-type-eYf5cS1Csw
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany
Subject
Medicine & Public Health; Internal Medicine; Metabolic Diseases; Human Physiology
ISSN
0012-186X
eISSN
1432-0428
D.O.I.
10.1007/s00125-017-4376-2
Publisher site
See Article on Publisher Site

Abstract

Diabetologia (2017) 60:1834–1835 DOI 10.1007/s00125-017-4376-2 RESEARCH LETTER Autoantibody binding in liquid phase to IL-2 in human sera is not type 1 diabetes specific 1 2 1 3 Ilaria Marzinotto & Daniela Liberati & Cristina Brigatti & Riccardo Bonfanti & 1 1 1,4 1,4 Angela Stabilini & Paolo Monti & Emanuele Bosi & Lorenzo Piemonti & Vito Lampasona Received: 30 May 2017 /Accepted: 13 June 2017 /Published online: 19 July 2017 Springer-Verlag GmbH Germany 2017 . . . . Keywords Autoantibodies Autoimmunity ELISA IL-2 locyte colony-stimulating factor, IL-6, IL-17 and IL-22, have . . Immunoprecipitation LIPS Type 1 diabetes been described in a variety of other diseases, including auto- immune syndromes sometimes presenting together with type 1 diabetes [2]. In an original report by Pérol et al [1], IL-2 auto- antibodies, measured by a direct ELISA assay, were suggested to be present in the NOD mouse, where they correlated with Abbreviations disease development, and in around 25% of humans at onset of LIPS Luciferase immunoprecipitation system type 1 diabetes. To investigate the presence of IL-2 autoanti- NLuc-IL-2 Recombinant IL-2 tagged with a NanoLuc bodies in human type 1 diabetes, we developed a novel assay luciferase reporter based on the luciferase

Journal

DiabetologiaSpringer Journals

Published: Jul 19, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off