Associations Between Past Alcohol, Cannabis, and Cocaine Use and Current Schizotypy Among First-Degree Relatives of Patients With Schizophrenia and Non-Psychiatric Controls

Associations Between Past Alcohol, Cannabis, and Cocaine Use and Current Schizotypy Among... Associations between past use of alcohol, cannabis, and cocaine and various domains of schizotypy were examined in first-degree relatives of patients with schizophrenia and non-psychiatric controls. Substance use was operationalized in three ways: (1) having ever used the substance, (2) age at first use, and (3) past frequency/amount of use during three time periods in late adolescence/early adulthood. Schizotypy was assessed using the Schizotypal Personality Questionnaire (SPQ). Participants who had ever used cannabis had significantly higher cognitive-perceptual, interpersonal, and total schizotypy scores compared to those who had not. Younger age of alcohol use onset was associated with more schizotypy in adulthood, and younger age of first cannabis use was related to more interpersonal schizotypy. More frequent/heavier use of alcohol in the 25–29 age-range, and cannabis in early adulthood, were associated with more schizotypy. The use of addictive substances, particularly cannabis, is related to schizotypy in complex ways. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Psychiatric Quarterly Springer Journals

Associations Between Past Alcohol, Cannabis, and Cocaine Use and Current Schizotypy Among First-Degree Relatives of Patients With Schizophrenia and Non-Psychiatric Controls

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Publisher
Springer Journals
Copyright
Copyright © 2009 by Springer Science+Business Media, LLC
Subject
Medicine & Public Health; Psychiatry; Public Health; Sociology, general
ISSN
0033-2720
eISSN
1573-6709
D.O.I.
10.1007/s11126-009-9102-x
Publisher site
See Article on Publisher Site

Abstract

Associations between past use of alcohol, cannabis, and cocaine and various domains of schizotypy were examined in first-degree relatives of patients with schizophrenia and non-psychiatric controls. Substance use was operationalized in three ways: (1) having ever used the substance, (2) age at first use, and (3) past frequency/amount of use during three time periods in late adolescence/early adulthood. Schizotypy was assessed using the Schizotypal Personality Questionnaire (SPQ). Participants who had ever used cannabis had significantly higher cognitive-perceptual, interpersonal, and total schizotypy scores compared to those who had not. Younger age of alcohol use onset was associated with more schizotypy in adulthood, and younger age of first cannabis use was related to more interpersonal schizotypy. More frequent/heavier use of alcohol in the 25–29 age-range, and cannabis in early adulthood, were associated with more schizotypy. The use of addictive substances, particularly cannabis, is related to schizotypy in complex ways.

Journal

Psychiatric QuarterlySpringer Journals

Published: Apr 25, 2009

References

  • Genetic and environmental influences on schizotypy: A community-based twin study
    MacDonald, AW; Pogue-Geile, MF; Debski, TT
  • A 10-year retrospective study of inpatient adolescents with schizophrenia/schizoaffective disorder and substance use
    Shoval, G; Zalsman, G; Apter, A
  • Axis I and Axis II comorbidity in alcohol dependence and the two types of alcoholism
    Driessen, M; Veltrup, C; Wetterling, T
  • Schizotypal personality disorder in an outpatient population: Incidence and clinical characteristics
    Bornstein, RF; Klein, DN; Mallon, JC
  • Cannabis use correlates with schizotypal personality traits in healthy students
    Dumas, P; Saoud, M; Bouafia, S
  • Symptoms of schizotypy precede cannabis use
    Schiffman, J; Nakamura, B; Earleywine, M
  • Cannabis use correlates with schizotypy in healthy people
    Williams, JH; Wellman, NA; Rawlins, JNP

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