Association of Single Nucleotide Polymorphisms in XRCC1 (194) and XPD (751) with Age-related cataract

Association of Single Nucleotide Polymorphisms in XRCC1 (194) and XPD (751) with Age-related... Int Ophthalmol (2018) 38:1135–1146 https://doi.org/10.1007/s10792-017-0574-7 ORIGINAL PAPER Association of Single Nucleotide Polymorphisms in XRCC1 (194) and XPD (751) with Age-related cataract . . . . . Tafheem Khosa Sana Aslam Saima Mustafa Atif Akbar Rehan Sadiq Shaikh Furhan Iqbal Received: 12 December 2016 / Accepted: 20 May 2017 / Published online: 30 May 2017 Springer Science+Business Media Dordrecht 2017 Abstract individually or in various combinations with the Purpose Age-related cataract (ARC) is a multifacto- studied epidemiological factors known to be associ- rial disease and different risk factors, including genetic ated with ARC. and environmental, are responsible for the development Results Our results indicated that both SNPs of its various types. The aim of this study was to find out Arg194Trp in XRCC1 (P = 0.967) and Lys751Gln a correlation, if any, between ARC and the single in XPD (P = 0.995) were not associated with ARC nucleotide polymorphisms (SNPs) in DNA repair genes whether they were analyzed individually or in com- XRCC1 (X-ray repair cross-complementary-1) bined form (P [ 0.05). Analysis of epidemiological [Arg194Trp (rs1799782)] and XPD (xerodermapig- factors revealed that age (P \ 0.001), cast of subjects mentosa complementation group D) [Lys751Gln (P = 0.001), diabetes (P\ 0.001), http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png International Ophthalmology Springer Journals

Association of Single Nucleotide Polymorphisms in XRCC1 (194) and XPD (751) with Age-related cataract

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Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer Science+Business Media Dordrecht
Subject
Medicine & Public Health; Ophthalmology
ISSN
0165-5701
eISSN
1573-2630
DOI
10.1007/s10792-017-0574-7
pmid
28560653
Publisher site
See Article on Publisher Site

Abstract

Int Ophthalmol (2018) 38:1135–1146 https://doi.org/10.1007/s10792-017-0574-7 ORIGINAL PAPER Association of Single Nucleotide Polymorphisms in XRCC1 (194) and XPD (751) with Age-related cataract . . . . . Tafheem Khosa Sana Aslam Saima Mustafa Atif Akbar Rehan Sadiq Shaikh Furhan Iqbal Received: 12 December 2016 / Accepted: 20 May 2017 / Published online: 30 May 2017 Springer Science+Business Media Dordrecht 2017 Abstract individually or in various combinations with the Purpose Age-related cataract (ARC) is a multifacto- studied epidemiological factors known to be associ- rial disease and different risk factors, including genetic ated with ARC. and environmental, are responsible for the development Results Our results indicated that both SNPs of its various types. The aim of this study was to find out Arg194Trp in XRCC1 (P = 0.967) and Lys751Gln a correlation, if any, between ARC and the single in XPD (P = 0.995) were not associated with ARC nucleotide polymorphisms (SNPs) in DNA repair genes whether they were analyzed individually or in com- XRCC1 (X-ray repair cross-complementary-1) bined form (P [ 0.05). Analysis of epidemiological [Arg194Trp (rs1799782)] and XPD (xerodermapig- factors revealed that age (P \ 0.001), cast of subjects mentosa complementation group D) [Lys751Gln (P = 0.001), diabetes (P\ 0.001),

Journal

International Ophthalmology – Springer Journals

Published: May 30, 2017

References

  • Age-related cataract
    Asbell, PA; Dualan, I; Mindel, J; Brocks, D; Ahmad, M; Epstein, S
  • Epidemiological correlates of cataract cases in tertiary health care center in rural area of Maharashtra
    Avachat, SS; Phalke, V; Kambale, S
  • Ocular immune privilege: the eye takes a dim but practical view of immunity and inflammation
    Streilein, JW
  • Ocular phototoxicity
    Roberts, JE
  • Age-related human nuclear cataract. a condition due to inexorable protein deterioration
    Truscott, J
  • Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-alpha) and essential hypertension
    Bautista, LE; Vera, LM; Arenas, IA; Gamrara, G
  • Efficacy of a capsular tension ring for phacoemulsification in eyes with zonular dialysis
    Agarwal, A; Agarwal, A; Jacob, S
  • Overweight, obesity, and age-related cataract: a meta-analysis
    Pan, CW; Lin, Y
  • Oxidative stress and age-related cataract
    Ottonello, S; Foroni, C; Carta, A; Petrucco, S; Maraini, G
  • Genetic polymorphisms in lung disease: bandwagon or breakthrough
    Ianuzzi, MC; Maliarik, M; Rybicki, B
  • Implications of XRCC1, XPD and APE1 gene polymorphism in north Indian population: a comparative approach in different ethnic groups worldwide
    Gangwar, R; Manchanda, PK; Mittal, RD
  • An overview of types of DNA damage and causal agents
    Helleday, T; Eshtad, S; Nik-Zainal, S
  • The DNA-damage response in human biology and disease
    Jackson, SP; Bartek, J
  • The DNA damage response: making it safe to play with knives
    Ciccia, A; Elledge, SJ
  • Polymorphisms in DNA repair genes and associations with cancer risk
    Goode, EL; Ulrich, CM; Potter, JD
  • DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma
    Povey, JE; Darakhshan, F; Robertson, K; Bisset, Y; Mekky, M; Rees, J; Doherty, V; Kavanagh, G; Anderson, N; Campbe, H; MacKie, M; Melton, DW
  • Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract
    Zhang, Y; Zhang, L; Song, Z; Sun, DL; Liu, HR; Song Bin, FuSB; Liu, DR; Liu, P
  • Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related cataract development in Han Chinese
    Luo, YF; Wang, BB; Zhou, Z; Ding, XC; Hu, SS; Zhou, GK; Ma, X; Qi, YH
  • Polymorphisms of DNA repair genes XPD and XRCC1 and risk of cataract development
    Ünal, M; Güven, M; Batar, B; Özaydın, A; Sarici, A; Devranoğlu, K
  • Polymorphisms of the DNA repair genes XPD and XRCC1 and the risk of age-related macular degeneration
    Güven, M; Unal, M; Batar, B; Güven, GS; Yenerel, M; Tatlipinar, S; Seven, M; Yüksel, A
  • Association of Polymorphisms (rs1799782, rs25489 and rs25487) in XRCC1 and (rs13181) XPD genes with acute coronary artery syndrome in subjects from Multan, Pakistan
    Hameed, H; Faryal, M; Aslam, MA; Akbar, A; Saad, AB; Pasha, MB; Latif, M; Shaikh, RS; Ali, M; Iqbal, F
  • Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk
    Smith, TR; Levine, EA; Freimanis, RI; Akman, SA; Allen, GO; Hoang, KN
  • Polymorphisms in nucleotide excision repair genes and risk of multiple primary melanoma: the genes environment and melanoma study
    Millikan, RC; Hummer, A; Begg, C; Player, J; Cotret, AR; Winkel, S
  • Human DNA repair genes
    Wood, RD; Mitchell, M; Sgouros, J; Lindahl, T
  • Polymorphisms in DNA repair genes and associations with cancer risk
    Goode, EL; Ulrich, CM; Potter, JD
  • ERCC2/XPD gene polymorphisms and cancer risk
    Benhamou, S; Sarasin, A
  • XRCC1 and DNA strand break repair
    Caldecott, KW
  • Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract
    Zhang, Y; Zhang, L; Song, Z; Sun, DL; Liu, HR; Fu, SB; Liu, DR; Liu, P
  • Epidemiologic study of age related cataracts among an elderly Chinese population in Shih-Pai, Taiwan
    Tsai, SY; Hsu, WM; Cheng, CY
  • Population-based study on prevalence and risk factors of age related cataracts in Peitou, Taiwan
    Cheng, CY; Liu, JH; Chen, SJ
  • Risk factors associated with incident cataracts and cataract surgery in the age-related eye disease study
    Chang, JR; Koo, E; Agrón, E; Hallak, J; Clemons, T
  • Sex hormones and their receptors in patients with age-related cataract
    Zhang, XI; Sun, HM; JI, J; Zhang, H; Jin, Z; Yuan, JI
  • Prevalence of cataract in an older population in India
    Vashist, P; Talwar, B; Gogoi, M; Maraini, G; Camparini, G; Ravindran, R; Murthy, G; Fitzpatrick, K; John, N; Chakravarthy, U; Ravilla, T; Fletcher, A
  • Drug use and 5-year incidence of age-related cataracts
    Klein, BE; Klein, R; Lee, KE; Danforth, LG
  • Prevalence of lens opacities in the Barbados Eye Study
    Leske, MC; Connell, AMS; Wu, SY
  • Diabetic cataract—pathogenesis, epidemiology and treatment
    Pollreisz, A; Schmidt-Erfurth, U
  • Prevalence and risk factors for cataract in diabetes: sankara nethralaya diabetic retinopathy epidemiology and molecular genetics study
    Raman, R; Pal, SS; Adams, K; Rani, PK; Vaitheeswaran, K; Sharma, T
  • A influence of hypertension and diabetes mellitus on senile cataract
    Shakil, M Ahmed; Samiullah, ST; Perveen, S; Sheikh, K; Humaira, S; Khoja, A
  • Metabolic syndrome components and age-related cataract: the Singapore Malay eye study
    Sabanayagam, C; Wang, JJ; Mitchell, P; Tan, AV; Tai, ES; Aung, T; Saw, SM; Wong, TV
  • Age-related nuclear cataract-oxidation is the key
    Truscott, RJ
  • Smoking and risk of age-related cataract: a meta-analysis
    Juan, Y; He, Jinjing; Wang, C; Wu, H; Shi, X; Zhang, H; Xie, J; Lee, SL
  • Cigarette smoking, body mass index associated with the risks of age-related cataract in male patients in northeast China
    Lu, ZQ; Sun, WH; Yan, J; Jiang, TX; Zhai, SN; Li, Y
  • Smoking, socioeconomic factors, and age-related cataract the Singapore Malay eye study
    Renyi, Wu; Wang, J; Mitchell, P; Lamoureux, ER; Zheng, Y; Rochtchina, E; Ava, G
  • The etiology of steroid cataract
    James, ER
  • Risk factors for cataract: a case control study
    Ughade, SN; Zodpey, SP; Khanolkar, VA
  • XRCC1 stimulates human polynucleotide kinase activity at damaged DNA termini and accelerates DNA single-strand break repair
    Whitehouse, CJ; Taylor, RM; Thistlethwaite, A; Zhang, H; Karimi-Busheri, F; Lasko, DD; Weinfeld, M; Caldecott, KW

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