Access the full text.
Sign up today, get DeepDyve free for 14 days.
E. Azmitia (1999)
Serotonin Neurons, Neuroplasticity, and Homeostasis of Neural TissueNeuropsychopharmacology, 21
J. Balciuniene, Q. Yuan, C. Engström, K. Lindblad, P. Nylander, M. Sundvall, M. Schalling, U. Pettersson, R. Adolfsson, E. Jazin (1998)
Linkage analysis of candidate loci in families with recurrent major depressionMolecular Psychiatry, 3
K. Lesch, U. Balling, J. Gross, K. Strauss, B. Wolozin, D. Murphy, P. Riederer (2005)
Organization of the human serotonin transporter geneJournal of Neural Transmission / General Section JNT, 95
(2004)
Human 5 - HT 1 A Receptor C ( - 1019 ) G Polymorphism and Phychopathology
D. Hranilovic, J. Štefulj, I. Furač, M. Kubat, M. Balija, B. Jernej (2003)
Serotonin transporter gene promoter (5-HTTLPR) and intron 2 (VNTR) polymorphisms in Croatian suicide victimsBiological Psychiatry, 54
J. Hauser, A. Leszczynska, J. Samochowiec, P. Czerski, A. Ostapowicz, M. Chlopocka, J. Horodnicki, J. Rybakowski (2003)
Association analysis of the insertion/deletion polymorphism in serotonin transporter gene in patients with affective disorderEuropean Psychiatry, 18
C.C. Mathew (1984)
Methods in Molecular Biology
P. Sullivan, M. Neale, K. Kendler (2000)
Genetic epidemiology of major depression: review and meta-analysis.The American journal of psychiatry, 157 10
(2002)
Associ - ation of a Polymorphism of the Serotonin 1 B Receptor Gene and Alcohol Dependence with Inactive Aldehydroge - nase - 2
R. Myers, D. Airey, D. Manier, Richard Shelton, E. sanders-Bush (2007)
Polymorphisms in the Regulatory Region of the Human Serotonin 5-HT2A Receptor Gene (HTR2A) Influence Gene ExpressionBiological Psychiatry, 61
(1994)
Classifica - tion of Receptors for 5 - Hydroxytryptamine ( Serotonin )
K. Ressler, C. Nemeroff (2000)
Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disordersDepression and Anxiety, 12
J. Lappalainen, J. Long, M. Eggert, N. Ozaki, R. Robin, Gerald Brown, H. Naukkarinen, M. Virkkunen, M. Linnoila, D. Goldman (1998)
Linkage of antisocial alcoholism to the serotonin 5-HT1B receptor gene in 2 populations.Archives of general psychiatry, 55 11
Yung-yu Huang, Cristina Battistuzzi, M. Oquendo, J. Harkavy-Friedman, L. Greenhill, G. Zalsman, B. Brodsky, V. Arango, D. Brent, J. Mann (2004)
Human 5-HT1A receptor C(-1019)G polymorphism and psychopathology.The international journal of neuropsychopharmacology, 7 4
D. Hoyer, D. Clarke, J. Fozard, P. Hartig, G. Martin, E. Mylecharane, P. Saxena, P. Humphrey (1994)
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).Pharmacological reviews, 46 2
E. Mundo, M. Richter, F. Sam, F. Macciardi, J. Kennedy (2000)
Is the 5-HT(1Dbeta) receptor gene implicated in the pathogenesis of obsessive-compulsive disorder?The American journal of psychiatry, 157 7
(2006)
Altered Serotonin 1 A Binding in Major Depression : A [ carbonyl - C - 11 ] WAY 100635 Positron Emission Tomograhpy Study
M. Jarrett, R. Kohen, K. Cain, R. Burr, A. Poppe, G. Navaja, M. Heitkemper (2007)
Relationship of SERT Polymorphisms to Depressive and Anxiety Symptoms in Irritable Bowel SyndromeBiological Research For Nursing, 9
S. Lemonde, G. Turecki, D. Bakish, L. Du, P. Hrdina, C. Bown, A. Sequeira, N. Kushwaha, S. Morris, A. Basak, X. Ou, P. Albert (2003)
Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and SuicideThe Journal of Neuroscience, 23
E. Gould (1999)
Serotonin and Hippocampal NeurogenesisNeuropsychopharmacology, 21
Y. Hasegawa, S. Higuchi, S. Matsushita, H. Miyaoka (2002)
Association of a polymorphism of the serotonin 1B receptor gene and alcohol dependence with inactive aldehyde dehydrogenase-2Journal of Neural Transmission, 109
S.G. Suakisyan, N.G. Manasyan, A.A. Babakhanyan (2006)
Effectiveness of Coaxil (Tianeptin) in Therapy of Depressive DisordersNeironauki, 6
Yung-yu Huang, M. Oquendo, J. Friedman, L. Greenhill, B. Brodsky, K. Malone, V. Khait, J. Mann (2003)
Substance Abuse Disorder and Major Depression are Associated with the Human 5-HT1B Receptor Gene (HTR1B) G861C PolymorphismNeuropsychopharmacology, 28
(2005)
Genetic Factors in Epidemiology and Pathogenesis of Unipolar Depression
T. Nakamura, S. Matsushita, N. Nishiguchi, M. Kimura, A. Yoshino, S. Higuchi (1999)
Association of a polymorphism of the 5HT2A receptor gene promoter region with alcohol dependenceMolecular Psychiatry, 4
A. Serretti, L. Mandelli, I. Giegling, B. Schneider, A. Hartmann, A. Schnabel, K. Maurer, H. Möller, D. Rujescu (2007)
HTR2C and HTR1A gene variants in German and Italian suicide attempters and completersAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 144B
E. Mundo, M. Richter, F. Sam, F. Macciardi, J. Kennedy (2000)
Is the 5-HT1Dβ Receptor Gene Implicated in the Pathogenesis of Obsessive-Compulsive Disorder?American Journal of Psychiatry, 157
Myoung-Jin Choi, Heon-Jeong Lee, Hong-Pyo Lee, B. Ham, J. Cha, S. Ryu, Min-Soo Lee (2004)
Association between Major Depressive Disorder and the –1438A/G Polymorphism of the Serotonin 2A Receptor GeneNeuropsychobiology, 49
Y. Yu, S. Tsai, Y. Liou, C. Hong, Tai‐Jui Chen (2006)
Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disordersEuropean Neuropsychopharmacology, 16
E. Mellerup, B. Bennike, T. Bolwig, H. Dam, L. Hasholt, M. Jørgensen, P. Plenge, Sven Sørensen (2001)
Platelet serotonin transporters and the transporter gene in control subjects, unipolar patients and bipolar patientsActa Psychiatrica Scandinavica, 103
D. Collier, G. Stöber, Tao Li, A. Heils, M. Catalano, D. Bella, M. Arranz, R. Murray, H. Vallada, D. Bengel, C. Müller, G. Roberts, E. Smeraldi, G. Kirov, P. Sham, K. Lesch (1996)
A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders.Molecular psychiatry, 1 6
(2003)
Association Study of the Serotonin 2 A and 1 B Receptor Genes with Suicidal Behavior in Two Different Populations from Russia
A. Ogilvie, S. Battersby, G. Fink, A. Harmar, G. Goodwin, V. Bubb, Cad Smith (1996)
Polymorphism in serotonin transporter gene associated with susceptibility to major depressionThe Lancet, 347
(1996)
Polymor - phism in Transporter Gene Associated with Susceptibility to Major Depression
A. Strobel, L. Gutknecht, C. Rothe, A. Reif, R. Mössner, Yong Zeng, B. Brocke, K. Lesch (2003)
Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traitsJournal of Neural Transmission, 110
P. Courtet, M. Picot, F. Bellivier, S. Torres, F. Jollant, C. Michelon, D. Castelnau, B. Astruc, C. Buresi, A. Malafosse (2003)
Serotonin transporter gene may be involved in short-term risk of subsequent suicide attemptsBiological Psychiatry, 55
R. Rieder, E. Donnelly, J. Herdt, I. Waldman (1979)
Sulcal prominence in young chronic schizophrenic patients: CT scan findings associated with impairment on neuropsychological testsPsychiatry Research, 1
R. Parsey, M. Oquendo, R. Ogden, D. Olvet, N. Simpson, Yung-yu Huang, R. Heertum, V. Arango, J. Mann (2006)
Altered Serotonin 1A Binding in Major Depression: A [carbonyl-C-11]WAY100635 Positron Emission Tomography StudyBiological Psychiatry, 59
E. Lovejoy, A. Scott, C. Fiskerstrand, V. Bubb, J. Quinn (2003)
The serotonin transporter intronic VNTR enhancer correlated with a predisposition to affective disorders has distinct regulatory elements within the domain based on the primary DNA sequence of the repeat unitEuropean Journal of Neuroscience, 17
L. Bierut, A. Heath, K. Bucholz, S. Dinwiddie, P. Madden, D. Statham, Michael Dunne, Nicholas Martin (1999)
Major depressive disorder in a community-based twin sample: are there different genetic and environmental contributions for men and women?Archives of general psychiatry, 56 6
C. Mathew (1985)
The isolation of high molecular weight eukaryotic DNA.Methods in molecular biology, 2
C. Fehr, Nina Grintschuk, A. Szegedi, I. Anghelescu, C. Klawe, P. Singer, C. Hiemke, N. Dahmen (2000)
The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsyPsychiatry Research, 97
A. Heils, A. Teufel, S. Petri, G. Stöber, P. Riederer, D. Bengel, K. Lesch (1996)
Allelic Variation of Human Serotonin Transporter Gene ExpressionJournal of Neurochemistry, 66
Yung-yu Huang, R. Grailhe, V. Arango, R. Hen, J. Mann (1999)
Relationship of Psychopathology to the Human Serotonin1B Genotype and Receptor Binding Kinetics in Postmortem Brain TissueNeuropsychopharmacology, 21
Serotoninergic system is one of the major brain neurotransmitter systems that is involved in the development of depressive spectrum disorders. Regulatory genes of this system are the principle candidate genes predisposing to unipolar depression. Using PCR-RFLP analysis, we have conducted a study of polymorphic loci of several genes of this system: C1019G of serotonin receptor 1A gene, (HTR1A); A-1438G of serotonin receptor 2A gene, (HTR2A); G861C of serotonin receptor 1B gene, (HTR1B); Stin2VNTR and 5-HTTLPR of serotonin transporter gene (SLC6A4) in patients with unipolar depression from Tatar and Russian population. The results of the study suggest that genotype 10/10 of the SLC6A4 gene as well as genotype G/G and allele G of the HTR2A gene can predispose to increased risk of unipolar depression development in ethnic Russians. In contrast, genotype 12/10 of the SLC6A4 gene is a marker of low risk of the disease in both groups.
Russian Journal of Genetics – Springer Journals
Published: Jun 19, 2009
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.