The distributions of the alleles and genotypes of polymorphic marker A1/A2 of gene ITGB3 encoding the β3 subunit of integrin αIIbβ3 in groups of patients with coronary artery disease (CAD), including those who have had myocardial infarction (MI), and in the control group have been compared. Analysis using Fisher's test has not revealed significant differences between these groups with respect to the distributions of the alleles and genotypes of polymorphic marker A1/A2 of gene ITGB3. This indicates that this polymorphic marker is not associated with either CAD or MI in the Moscow population.
Russian Journal of Genetics – Springer Journals
Published: Oct 29, 2004
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