Present study estimated certain blood energy metabolites during peri-partum period in crossbred cows that did and did not develop post-partum puerperal metritis (PM) and analyzed their association with ensuing PM. Glucose, total-cholesterol, urea-nitrogen (PUN), non-esterified fatty acids (NEFA) and β-hydroxybutyrate (BHBA) concentrations were estimated in blood plasma samples collected from pluriparous cows (n = 20) at 2 (wk-2) and 1 week (wk-1) before expected date of calving, on d + 1, d + 7 and d + 14 after calving. The PM cows had significantly lower glucose but higher BHBA than normal cows between d + 1 and d + 14. Between wk-2 to d + 14, PM cows had significantly lower total-cholesterol but higher NEFA and NEFA:total-cholesterol ratio than healthy cows. Moreover, PUN:BHBA ratio was significantly lower in PM cows than normal cows on d + 14. Receiver-operating characteristic analysis indicated that NEFA:total-cholesterol ratio had higher area under curve (AUC) at wk-2 (AUC = 0.91) and wk-1 (AUC = 0.96) than other metabolites. However, as compared to other metabolites, AUC was higher on d + 1 (AUC = 0.92) and on d + 7 (AUC = 0.98) for NEFA and on d + 14 (AUC = 1.0) for BHBA. Estimated risk ratio values indicated that NEFA:total-cholesterol ratio at wk-2 and wk-1 were significantly associated with 8.55 times higher risk of PM than other metabolites. Moreover, NEFA, BHBA and NEFA:total-cholesterol values were associated with >8.55 times higher risk of PM during post-partum period. Thus, it may be concluded that cows, which developed PM suffered with negative energy balance around parturition. Ratio of NEFA: total-cholesterol at wk-2 and wk-1 could be helpful for early identification of PM with higher accuracy in crossbred cows.
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences – Springer Journals
Published: May 21, 2016
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera