Combined palmar, plantar and penile contracture with knuckle pads is reported in the same patient. These are the different phenotypical manifestations of a common disorder originating in a genetic alteration of connective tissue. However, the simultaneous presentation of all these pathological signs in a single patient is extremely rare, and may be closely correlated to increased aggressiveness of the disease, as reflected by the evolution of the clinical case described.
European Journal of Plastic Surgery – Springer Journals
Published: Jan 21, 1998
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