Access the full text.
Sign up today, get DeepDyve free for 14 days.
Frank Middleton, M. Pato, M. Pato, K. Gentile, C. Morley, X. Zhao, A. Eisener, A. Brown, T. Petryshen, A. Kirby, A. Kirby, H. Medeiros, H. Medeiros, C. Carvalho, A. Macedo, A. Dourado, I. Coelho, J. Valente, M. Soares, C. Ferreira, M. Lei, M. Azevedo, James Kennedy, Mark Daly, Pamela Sklar, Pamela Sklar, C. Pato (2004)
Genomewide linkage analysis of bipolar disorder by use of a high-density single-nucleotide-polymorphism (SNP) genotyping assay: a comparison with microsatellite marker assays and finding of significant linkage to chromosome 6q22.American journal of human genetics, 74 5
A. Serretti, R. Lilli, C. Lorenzi, E. Lattuada, C. Cusin, E. Smeraldi (2001)
Tryptophan hydroxylase gene and major psychosesPsychiatry Research, 103
J. Vincent, M. Masellis, J. Lawrence, V. Choi, H. Gurling, S. Parikh, J. Kennedy (1999)
Genetic association analysis of serotonin system genes in bipolar affective disorder.The American journal of psychiatry, 156 1
D. Rubinsztein, J. Leggo, S. Goodburn, Craig Walsh, Sanjeev Jain, E. Paykel (1996)
Genetic association between monoamine oxidase A microsatellite and RFLP alleles and bipolar affective disorder: analysis and meta-analysis.Human molecular genetics, 5 6
V. Arango, Yung-yu Huang, M. Underwood, J. Mann (2003)
Genetics of the serotonergic system in suicidal behavior.Journal of psychiatric research, 37 5
A. Paoloni-Giacobino, D. Mouthon, Carmen Lambercy, M. Vessaz, S. Coutant-Zimmerli, W. Rudolph, A. Malafosse, C. Buresi (2000)
Identification and analysis of new sequence variants in the human tryptophan hydroxylase (TpH) geneMolecular Psychiatry, 5
M. Baron (2002)
Manic-depression genes and the new millennium: poised for discoveryMolecular Psychiatry, 7
S. Boularand, M. Darmon, Y. Ganem, J. Launay, J. Mallet (1990)
Complete coding sequence of human tryptophan hydroxylase.Nucleic acids research, 18 14
N. Varney (1996)
Psychopharmacology: The Fourth Generation of Progress.Psyccritiques, 41
A. McQuillin, N. Bass, G. Kalsi, J. Lawrence, V. Puri, K. Choudhury, S. Detera-Wadleigh, David Curtis, H. Gurling (2006)
Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3Molecular Psychiatry, 11
H. Cho, I. Meira-Lima, Q. Cordeiro, Leandro Michelon, P. Sham, H. Vallada, D. Collier (2005)
Population-based and family-based studies on the serotonin transporter gene polymorphisms and bipolar disorder: a systematic review and meta-analysisMolecular Psychiatry, 10
C. Friddle, C. Friddle, R. Koskela, R. Koskela, R. Koskela, Koustubh Ranade, Joan Hebert, Michele Cargill, Michele Cargill, Chris Clark, Melvin McInnis, S. Simpson, Francis McMahon, O. Stine, D. Meyers, Jianfeng Xu, Jianfeng Xu, D. MacKinnon, Theresa Swift-Scanlan, K. Jamison, S. Folstein, Mark Daly, Leonid Kruglyak, T. Marr, J. DePaulo, David Botstein (2000)
Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype.American journal of human genetics, 66 1
D. Gaysina, R. Leopardi, R. Gizatullin, E. Juriev, Rail Gabdulhakov, E. Khusnutdinova (2006)
Haplotype analysis of the TPH gene and association with suicidal behaviour in Russian males and femalesAnnals of General Psychiatry, 5
Christine Chen, S. Glatt, M. Tsuang (2008)
The tryptophan hydroxylase gene influences risk for bipolar disorder but not major depressive disorder: results of meta-analyses.Bipolar disorders, 10 7
F. Bellivier, M. Leboyer, P. Courtet, C. Buresi, B. Beaufils, D. Samolyk, J. Allilaire, J. Feingold, J. Mallet, A. Malafosse (1998)
Association between the tryptophan hydroxylase gene and manic-depressive illness.Archives of general psychiatry, 55 1
Fatemeh Haghighi, Helene Bach-Mizrachi, Yung-yu Huang, V. Arango, S. Shi, A. Dwork, G. Rosoklija, Huitao Sheng, Irina Morozova, Jingyue Ju, James Russo, J. Mann (2008)
Genetic architecture of the human tryptophan hydroxylase 2 Gene: existence of neural isoforms and relevance for major depressionMolecular Psychiatry, 13
F. Bloom, D. Kupfer (1995)
Psychopharmacology: The Fourth Generation of Progress
M. Preisig, F. Bellivier, B. Fenton, P. Baud, A. Berney, P. Courtet, P. Hardy, J. Golaz, M. Leboyer, J. Mallet, Marie-Louise Matthey, D. Mouthon, E. Neidhart, M. Nosten-Bertrand, Emmanuelle Stadelmann-Dubuis, J. Guimón, Fran殩s Ferrero, C. Buresi, A. Malafosse (2000)
Association between bipolar disorder and monoamine oxidase A gene polymorphisms: results of a multicenter study.The American journal of psychiatry, 157 6
Dawei Li, Lin He (2006)
Meta-analysis shows association between the tryptophan hydroxylase (TPH) gene and schizophreniaHuman Genetics, 120
L. Oruč, G. Verheyen, Ivana Furač, Miro Jakovljević, S. Ivezić, P. Raeymaekers, C. Broeckhoven (1997)
Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder.American journal of medical genetics, 74 5
Ian Blair, Ian Blair, A. Chetcuti, R. Badenhop, A. Scimone, M. Moses, L. Adams, N. Craddock, Elaine Green, G. Kirov, M. Owen, John Kwok, John Kwok, Jennifer Donald, P. Mitchell, P. Mitchell, Peter Schofield (2006)
Positional cloning, association analysis and expression studies provide convergent evidence that the cadherin gene FAT contains a bipolar disorder susceptibility alleleMolecular Psychiatry, 11
D. MacKinnon, K. Jamison, J. DePaulo (1997)
Genetics of manic depressive illness.Annual review of neuroscience, 20
M. McInnis, M. McInnis, T. Lan, T. Lan, V. Willour, F. McMahon, F. McMahon, S. Simpson, A. Addington, D. MacKinnon, J. Potash, A. Mahoney, J. Chellis, Y. Huo, T. Swift-Scanlan, H. Chen, R. Koskela, O. Stine, O. Stine, K. Jamison, P. Holmans, S. Folstein, K. Ranade, C. Friddle, D. Botstein, T. Marr, T. Beaty, Peter Zandi, J. DePaulo (2003)
Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12Molecular Psychiatry, 8
Lionel Lim, John Powell, Pak Sham, David Castle, Neil Hunt, R. Murray, Michael Gill (1995)
Evidence for a genetic association between alleles of monoamine oxidase A gene and bipolar affective disorder.American journal of medical genetics, 60 4
K. Lindblad, P. Nylander, A. Bruyn, Daniel Sourey, C. Zander, C. Engström, G. Holmgren, T. Hudson, J. Chotai, J. Mendlewicz, C. Broeckhoven, M. Schalling, R. Adolfsson (1995)
Detection of expanded CAG repeats in Bipolar Affective Disorder using the repeat expansion detection (RED) methodNeurobiology of Disease, 2
Tryptophan hydroxylase is one of the key enzymes involved in serotonergic metabolism. In many studies, an association between the TpH gene and human mentality, as well as mental disorders was demonstrated. This study was designed to analyze the association between three TpH gene polymorphisms (A218C, T3792A, and (CT) n (CA) n (CT) n ) and endogenous psychoses. The patients included into investigation were represented by those with manic-depressive psychosis (93 individuals) and those with the schizophrenia spectrum disorders (307 individuals). An association between the A218C polymorphism with the disorders of the schizophrenia spectrum was demonstrated. These findings confirmed the data obtained earlier for other populations. In addition, an association between the (CT) n (CA) n (CT) n microsatellite repeats and bipolar disease was shown for the first time.
Russian Journal of Genetics – Springer Journals
Published: Dec 12, 2009
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.