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Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes... Diabetes Ther (2018) 9:1269–1277 https://doi.org/10.1007/s13300-018-0436-y ORIGINAL RESEARCH Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis . . . . Xia Dai Zu-chun Luo Lu Zhai Wen-piao Zhao Feng Huang Received: April 13, 2018 / Published online: May 9, 2018 The Author(s) 2018 Methods: Electronic databases were carefully ABSTRACT searched for English publications comparing artificial pancreas with its control group. Over- Introduction: Insulin injection is the main all daytime and nighttime glucose parameters treatment in patients with type 1 diabetes mel- were considered as the endpoints. Data were litus (T1DM). Even though continuous glucose evaluated by means of weighted mean differ- monitoring has significantly improved the ences (WMDs) and 95% confidence intervals conditions of these patients, limitations still (CIs) generated by RevMan 5.3 software. exist. To further enhance glucose control in Results: A total number of 354 patients were patients with T1DM, an artificial pancreas has included. Artificial pancreas significantly main- been developed. We aimed to systematically tained a better mean concentration of glucose compare artificial pancreas with its control (WMD - 1.03, 95% CI - 1.32 to - 0.75; P = group during a 24-h basis in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetes Therapy Springer Journals

Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis

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Publisher
Springer Journals
Copyright
Copyright © 2018 by The Author(s)
Subject
Medicine & Public Health; Internal Medicine; Diabetes; Cardiology; Endocrinology
ISSN
1869-6953
eISSN
1869-6961
DOI
10.1007/s13300-018-0436-y
Publisher site
See Article on Publisher Site

Abstract

Diabetes Ther (2018) 9:1269–1277 https://doi.org/10.1007/s13300-018-0436-y ORIGINAL RESEARCH Artificial Pancreas as an Effective and Safe Alternative in Patients with Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis . . . . Xia Dai Zu-chun Luo Lu Zhai Wen-piao Zhao Feng Huang Received: April 13, 2018 / Published online: May 9, 2018 The Author(s) 2018 Methods: Electronic databases were carefully ABSTRACT searched for English publications comparing artificial pancreas with its control group. Over- Introduction: Insulin injection is the main all daytime and nighttime glucose parameters treatment in patients with type 1 diabetes mel- were considered as the endpoints. Data were litus (T1DM). Even though continuous glucose evaluated by means of weighted mean differ- monitoring has significantly improved the ences (WMDs) and 95% confidence intervals conditions of these patients, limitations still (CIs) generated by RevMan 5.3 software. exist. To further enhance glucose control in Results: A total number of 354 patients were patients with T1DM, an artificial pancreas has included. Artificial pancreas significantly main- been developed. We aimed to systematically tained a better mean concentration of glucose compare artificial pancreas with its control (WMD - 1.03, 95% CI - 1.32 to - 0.75; P = group during a 24-h basis in

Journal

Diabetes TherapySpringer Journals

Published: May 9, 2018

References