As an initial step to better define heart-brachial pulse wave velocity (hbPWV), a novel measure of proximal aortic stiffness, we proposed and validated a simple formula to estimate the arterial path length (Lhb) for hbPWV. In 190 patients aged 19–79 years, the reference Lhb was measured by a three-dimensional MRI. Using multiple regression analysis and fivefold cross-validation, estimation formulae were created using age, sex, and height. hbPWV was calculated as Lhb divided by the time interval from the second heart sound to the dicrotic notch on the brachial pressure wave. In a comparison of hbPWV calculated from MRI-based Lhb, strong correlations and accuracy were observed for the hbPWV obtained from the estimated Lhb by sex and height (r = 0.969, −0.05 ± 0.54 m per s of the mean difference), and even greater correlations and accuracy were observed for the estimated value by age, sex, and height (r = 0.976, 0.00 ± 0.43 m per s of the mean difference). hbPWV values obtained from the straight distance method and the height-based equation showed significant biases with mean differences of 2.64 ± 0.94 and 2.53 ± 0.94 m per s. hbPWV could be evaluated accurately by the simple equation to estimate Lhb.
Hypertension Research – Springer Journals
Published: Mar 14, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera