Arterial path length estimation for heart-to-brachium pulse wave velocity

Arterial path length estimation for heart-to-brachium pulse wave velocity As an initial step to better define heart-brachial pulse wave velocity (hbPWV), a novel measure of proximal aortic stiffness, we proposed and validated a simple formula to estimate the arterial path length (Lhb) for hbPWV. In 190 patients aged 19–79 years, the reference Lhb was measured by a three-dimensional MRI. Using multiple regression analysis and fivefold cross-validation, estimation formulae were created using age, sex, and height. hbPWV was calculated as Lhb divided by the time interval from the second heart sound to the dicrotic notch on the brachial pressure wave. In a comparison of hbPWV calculated from MRI-based Lhb, strong correlations and accuracy were observed for the hbPWV obtained from the estimated Lhb by sex and height (r = 0.969, −0.05 ± 0.54 m per s of the mean difference), and even greater correlations and accuracy were observed for the estimated value by age, sex, and height (r = 0.976, 0.00 ± 0.43 m per s of the mean difference). hbPWV values obtained from the straight distance method and the height-based equation showed significant biases with mean differences of 2.64 ± 0.94 and 2.53 ± 0.94 m per s. hbPWV could be evaluated accurately by the simple equation to estimate Lhb. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Hypertension Research Springer Journals

Arterial path length estimation for heart-to-brachium pulse wave velocity

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Publisher
Nature Publishing Group UK
Copyright
Copyright © 2018 by The Japanese Society of Hypertension
Subject
Medicine & Public Health; Medicine/Public Health, general; Internal Medicine; Public Health; Geriatrics/Gerontology; Obstetrics/Perinatology/Midwifery; Health Promotion and Disease Prevention
ISSN
0916-9636
eISSN
1348-4214
D.O.I.
10.1038/s41440-018-0019-3
Publisher site
See Article on Publisher Site

Abstract

As an initial step to better define heart-brachial pulse wave velocity (hbPWV), a novel measure of proximal aortic stiffness, we proposed and validated a simple formula to estimate the arterial path length (Lhb) for hbPWV. In 190 patients aged 19–79 years, the reference Lhb was measured by a three-dimensional MRI. Using multiple regression analysis and fivefold cross-validation, estimation formulae were created using age, sex, and height. hbPWV was calculated as Lhb divided by the time interval from the second heart sound to the dicrotic notch on the brachial pressure wave. In a comparison of hbPWV calculated from MRI-based Lhb, strong correlations and accuracy were observed for the hbPWV obtained from the estimated Lhb by sex and height (r = 0.969, −0.05 ± 0.54 m per s of the mean difference), and even greater correlations and accuracy were observed for the estimated value by age, sex, and height (r = 0.976, 0.00 ± 0.43 m per s of the mean difference). hbPWV values obtained from the straight distance method and the height-based equation showed significant biases with mean differences of 2.64 ± 0.94 and 2.53 ± 0.94 m per s. hbPWV could be evaluated accurately by the simple equation to estimate Lhb.

Journal

Hypertension ResearchSpringer Journals

Published: Mar 14, 2018

References

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