Apatinib Reactions 1680, p51 - 2 Dec 2017 Multiple skin rash and oral ulcers: case report An adult man [age at the time of reaction onset not stated] developed multiple skin rash and oral ulcers during treatment with apatinib [route not stated]. The man, who was diagnosed with renal epithelioid angiomyolipoma with liver and abdomen metastasis, started receiving treatment with apatinib 500 mg/day on 10 January 2016. After two week of apatinib therapy, he developed apparent level III side effects, which included multiple skin rash and oral ulcers. His apatinib dose was reduced to half [outcomes not stated]. Author comment: "After 2 weeks of [apatinib], his appetite and abdominal distension improved, but he demonstrated apparent level III side effects, including multiple skin rash and oral ulcers, thus, the dosage was reduced by half." Ge X, et al. Successful treatment of liver and abdomen metastasis of renal epithelioid angiomyolipoma with apatinib: A case report. Translational Cancer Research 6: 1015-1019, No. 5, Oct 2017. Available from: URL: http:// doi.org/10.21037/tcr.2017.08.41 - China 803284665 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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