Antimicrobial pyrazole dyes: synthesis, characterization, and absorption characteristics

Antimicrobial pyrazole dyes: synthesis, characterization, and absorption characteristics Twenty-one novel pyrazole azo compounds were synthesized by coupling 3-amino-5-hydroxy-1H-pyrazole and 3-amino-1-phenyl-2-pyrazoline-5-one with diazonium salts derived from aniline, o, m, and p-nitroaniline, o and p-methoxyaniline, o, m, and p-chloroaniline, and o, m, and p-methylaniline. Spectroscopic data for these dyes, dissolved in six solvents, were measured. The effects of acid and base on the visible absorption spectra of the dyes are also reported. The structures of all the compounds were confirmed by Fourier-transform infrared spectroscopy, mass spectroscopy, ultraviolet and visible electronic absorption spectroscopy, nuclear magnetic resonance spectroscopy, and elemental analysis. In addition, the antimicrobial activity of the dyes against six pathogenic bacteria were examined in detail. Research on Chemical Intermediates Springer Journals

Antimicrobial pyrazole dyes: synthesis, characterization, and absorption characteristics

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Springer Netherlands
Copyright © 2013 by Springer Science+Business Media Dordrecht
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
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