Objectives To investigate the additional influence of either applied aPDT system nor MC showed a significant addi- antimicrobial photodynamic therapy (aPDT; Helbo® tional influence on clinical and microbiological healing Photodynamic Systems) or local application of minocycline outcomes in deep periodontal pockets compared to SRP microspheres (MC; Arestin, OraPharma) on clinical and mi- alone. crobiological healing results in deep periodontal pockets (PPD Clinical relevance In deep periodontal defects, the efficacy of non-surgical periodontal treatment seems not to be improved ≥6 mm) following non-surgical periodontal therapy (SRP). Materials and methods Forty-five patients with chronic peri- by adjunctive use of antimicrobial photodynamic therapy or odontitis were evaluated: test group aPDT + SRP (n =15), minocycline microspheres. positive control group MC + SRP (n =15), and negative control group SRP-alone (n = 15). Clinical and microbiolog- Keywords Antimicrobial photodynamic therapy . . ical healing parameters were recorded in every patient for four Non-surgical periodontal therapy Minocycline Local experimental teeth at baseline, 6 weeks, and 3, 6, and antibiotics Scaling and root planing 12 months. Wilcoxon signed-rank test and Mann-Whitney U test were used for statistical analysis (α =0.05). Results Significant improvements in clinical and microbio- Introduction logical parameters were found for all groups
Clinical Oral Investigations – Springer Journals
Published: Dec 1, 2016
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