Anticoagulation therapy for a LVAD patient with acquired warfarin resistance

Anticoagulation therapy for a LVAD patient with acquired warfarin resistance Anticoagulation therapy with warfarin is essential for postoperative management in patients with left ventricular assist device (LVAD). In this manuscript, we report the case of a patient who developed warfarin resistance after LVAD implantation. Although we administered a novel anticoagulant drug in addition to warfarin and aspirin therapy, the patient developed a major stroke. The patient needed continuous intravenous heparinization until heart transplantation for approximately 2 years. Meticulous management of anticoagulation therapy is essential for a LVAD with warfarin resistance. To our best knowledge, our case is the first case of warfarin resistance in a patient with LVAD. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Artificial Organs Springer Journals

Anticoagulation therapy for a LVAD patient with acquired warfarin resistance

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Publisher
Springer Japan
Copyright
Copyright © 2017 by The Japanese Society for Artificial Organs
Subject
Medicine & Public Health; Cardiac Surgery; Nephrology; Biomedical Engineering
ISSN
1434-7229
eISSN
1619-0904
D.O.I.
10.1007/s10047-017-0947-8
Publisher site
See Article on Publisher Site

Abstract

Anticoagulation therapy with warfarin is essential for postoperative management in patients with left ventricular assist device (LVAD). In this manuscript, we report the case of a patient who developed warfarin resistance after LVAD implantation. Although we administered a novel anticoagulant drug in addition to warfarin and aspirin therapy, the patient developed a major stroke. The patient needed continuous intravenous heparinization until heart transplantation for approximately 2 years. Meticulous management of anticoagulation therapy is essential for a LVAD with warfarin resistance. To our best knowledge, our case is the first case of warfarin resistance in a patient with LVAD.

Journal

Journal of Artificial OrgansSpringer Journals

Published: Mar 27, 2017

References

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