Anti-fibronectin aptamers improve the colonization of chitosan films modified with D-(+) Raffinose by murine osteoblastic cells

Anti-fibronectin aptamers improve the colonization of chitosan films modified with D-(+)... J Mater Sci: Mater Med (2017) 28:136 DOI 10.1007/s10856-017-5931-6 TISSUE ENGINEERING CONSTRUCTS AND CELL SUBSTRATES Original Research Anti-fibronectin aptamers improve the colonization of chitosan films modified with D-(+) Raffinose by murine osteoblastic cells 1,2 1,2,3 4 3 4 2 ● ● ● ● ● ● L. Parisi C. Galli A. Bianchera P. Lagonegro L. Elviri A. Smerieri 1,2 1,2 4 1,2,3 ● ● ● S. Lumetti E. Manfredi R. Bettini G. M. Macaluso Received: 12 January 2017 / Accepted: 20 June 2017 / Published online: 31 July 2017 © Springer Science+Business Media, LLC 2017 Abstract The aim of the present study was to investigate amount of adsorbed fibronectin, but affected osteoblasts how the enrichment of chitosan films with anti-fibronectin behavior. Cell growth was proportional to the amount of aptamers could enhance scaffold colonization by osteo- aptamer used for the functionalization, as well as aptamers blasts, by improving their adhesion and accelerating their influenced cell morphology and their adhesion to the sub- proliferation. Chitosan discs were enriched with excess of strate. Our results demonstrate that the enrichment of chit- anti-fibronectin aptamer. Aptamer adsorption on chitosan osan films with aptamers could selectively improve was monitored by measuring aptamer concentration in the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Materials Science: Materials in Medicine Springer Journals

Anti-fibronectin aptamers improve the colonization of chitosan films modified with D-(+) Raffinose by murine osteoblastic cells

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Publisher
Springer US
Copyright
Copyright © 2017 by Springer Science+Business Media, LLC
Subject
Materials Science; Biomaterials; Biomedical Engineering; Regenerative Medicine/Tissue Engineering; Polymer Sciences; Ceramics, Glass, Composites, Natural Materials; Surfaces and Interfaces, Thin Films
ISSN
0957-4530
eISSN
1573-4838
D.O.I.
10.1007/s10856-017-5931-6
Publisher site
See Article on Publisher Site

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