To analyze the copies of the suffix short retroelement, its homologs were searched in nucleic acid sequence databases of the Drosophila melanogastergenome. The search yielded several conserved (near identical in sequence) copies, which are indicative of recent suffix transposition, and numerous divergent copies, which suggest ancientsuffix transposition. Analysis of the short suffix ORF revealed a conserved protein domain, which was also found as the eighth C-terminal domain in reverse transcriptases of certain long interspersed elements (LINEs). The suffix-encoded polypeptide proved to be homologous to DNA- and RNA-recognizing domains.
Russian Journal of Genetics – Springer Journals
Published: Oct 13, 2004
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