An integrated physical and genetic map of the PLS locus interval on Chromosome 11q14

An integrated physical and genetic map of the PLS locus interval on Chromosome 11q14 Mammalian Genome 11, 243–246 (2000). Incorporating Mouse Genome © Springer-Verlag New York Inc. 2000 An integrated physical and genetic map of the PLS locus interval on Chromosome 11q14 1, 1 2 1 1 Thomas C. Hart, * Stephen J. Walker, Donald W. Bowden, Patricia S. Hart, Scott A. Callison, 1 3 Peggy L. Bobby, Erhan Firatli Department of Pediatrics, Wake Forest University School of Medicine, Medical Center Bldg., Winston Salem, North Carolina, 27157, USA Department of Biochemistry, Wake Forest University School of Medicine, Medical Center Blvd., Winston Salem, North Carolina, 27157, USA Department of Periodontology, University of Istanbul, Istanbul, Turkey Received: 8 August 1999 / Accepted: 11 November 1999 Papillon Lefevre syndrome (PLS) is an autosomal recessive con- were downloaded from the Centre d’Etude du Polymorphisme Hu- dition characterized by palmoplantar hyperkeratosis and severe, main (CEPH) genotype database version 8.2 (http://landru.cephb. early-onset periodontitis that results in premature exfoliation of the fr/cephdb/). CEPH maintains a database of genotypes for all ge- primary and secondary dentitions (MIM#245000). Three groups netic markers that have been typed in the CEPH reference families have independently localized a major locus for PLS to overlapping for linkage mapping of the human chromosomes (Dausset et al. genetic http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Mammalian Genome Springer Journals

An integrated physical and genetic map of the PLS locus interval on Chromosome 11q14

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Publisher
Springer-Verlag
Copyright
Copyright © 2000 by Springer-Verlag New York Inc.
Subject
Life Sciences; Cell Biology; Anatomy; Zoology
ISSN
0938-8990
eISSN
1432-1777
D.O.I.
10.1007/s003350010046
Publisher site
See Article on Publisher Site

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