An electrochemical chiral sensor based on amino-functionalized graphene quantum dots/β-cyclodextrin modified glassy carbon electrode for enantioselective detection of tryptophan isomers

An electrochemical chiral sensor based on amino-functionalized graphene quantum... An electrochemical chiral sensing platform based on amino-functionalized graphene quantum dots/β-cyclodextrin modified glassy carbon electrode (NH2-GQDs/β-CD/GCE) was developed for enantioselective detection of tryptophan (Trp) isomers. NH2-GQDs/β-CD/GCE showed high electrocatalytic activity and good analytical behavior toward the oxidation of Trp isomers. The oxidation peak potentials and oxidation peak currents of Trp isomers at NH2-GQDs/β-CD/GCE surface were observed by differential pulse voltammetry. NH2-GQDs/β-CD nanocomposite exhibited different binding ability for two Trp isomers and selectively bonded with d-Trp, resulting in the higher oxidation peak current of d-Trp at NH2-GQDs/β-CD/GCE surface. Trp isomers exhibited different oxidation peak potentials at NH2-GQDs/β-CD/GCE surface, and the peak potential separation between l-Trp and d-Trp was around 0.022 V, which was used for the enantioselective detection of Trp isomers. Under the optimum experimental conditions, the oxidation peak currents were linearly dependent on the concentrations of Trp isomers. The linear ranges of l-Trp and d-Trp were all from 1.0 to 30.0 μM with correlation coefficients of 0.9886 and 0.9800, respectively. The detection limits of l-Trp and d-Trp were 0.65 and 0.12 μM (3σ/K), respectively. Such NH2-GQDs/β-CD/GCE displayed high anti-interference against some physiological substances, good reproducibility and excellent long-term stability toward Trp isomers detection in biomedical applications. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of the Iranian Chemical Society Springer Journals

An electrochemical chiral sensor based on amino-functionalized graphene quantum dots/β-cyclodextrin modified glassy carbon electrode for enantioselective detection of tryptophan isomers

Loading next page...
 
/lp/springer_journal/an-electrochemical-chiral-sensor-based-on-amino-functionalized-LReAIVHYmu
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Iranian Chemical Society
Subject
Chemistry; Analytical Chemistry; Inorganic Chemistry; Physical Chemistry; Biochemistry, general; Organic Chemistry
ISSN
1735-207X
eISSN
1735-2428
D.O.I.
10.1007/s13738-017-1134-9
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial