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- Publisher
- Springer Journals
- Copyright
- Copyright © 2017 by Springer Science+Business Media Dordrecht
- Subject
- Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
- ISSN
- 0922-6168
- eISSN
- 1568-5675
- DOI
- 10.1007/s11164-017-2896-5
- Publisher site
- See Article on Publisher Site
Abstract
A simple, efficient and convenient approach has been reported for the synthesis of quinazolines by the condensation of 3-amino, 1,2,4-triazole with dimedone and different aromatic aldehydes in the presence of anthranilic acid as a catalyst through a one-pot reaction. The high yield, at low cost, with no need of chromatographic separation, and the environmentally friendly catalyst are the prominent features of this protocol. The zwitterion of anthranilic acid plays an important role in this one-pot reaction.
Journal
Research on Chemical Intermediates – Springer Journals
Published: Feb 13, 2017